> Klotho beta (KLB)
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UGID:141383     UniGene Hs.90756     Homo sapiens (human)   KLB Order cDNA clone, Links
Klotho beta (KLB)

Human protein-coding gene KLB. Represented by 43 ESTs from 20 cDNA libraries. EST representation biased toward fetus. Corresponds to reference sequence NM_175737.3. [UniGene 141383 - Hs.90756]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_783864.1 KLB gene product H. sapiens 100.0 1043
XP_526550.1 PREDICTED: beta-klotho isoform 2 P. troglodytes 99.5 1043
NP_112457.1 Klb gene product M. musculus 79.5 1037
XP_001336584.4 PREDICTED: beta-klotho-like D. rerio 47.2 737
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
XP_003898640.1 PREDICTED: beta-klotho isoform 1 P. anubis 98.2 730
XP_001091413.1 PREDICTED: beta-klotho isoform 1 M. mulatta 97.8 1043

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: fetus [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; mammary gland; liver; mixed; uncharacterized tissue; adipose tissue; brain; eye; spleen
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4p14
UniSTS entry: Chr 4 SHGC-67244 [Map Viewer]
UniSTS entry: Chr 1 D15S1477
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

AB079373.1 Homo sapiens mRNA for klotho beta like protein, complete cds P
NM_175737.3 Homo sapiens klotho beta (KLB), mRNA PA
BC104871.1 Homo sapiens klotho beta, mRNA (cDNA clone MGC:132531 IMAGE:8143874), complete cds P
BC113653.1 Homo sapiens klotho beta, mRNA (cDNA clone MGC:142213 IMAGE:8322705), complete cds P
AK302436.1 Homo sapiens cDNA FLJ50094 complete cds, highly similar to Beta klotho P
BC033021.1 Homo sapiens klotho beta, mRNA (cDNA clone IMAGE:4824602), partial cds PA
BC143575.1 Homo sapiens klotho beta, mRNA (cDNA clone MGC:177103 IMAGE:9052086), complete cds P

EST sequences (10 of 43) [Show all sequences]

AI150491.1 Clone IMAGE:1752079 testis 3' read
BX097669.1 Clone IMAGp998O05261_;_IMAGE:161884 mammary gland A
BX089923.1 Clone IMAGp998B11422_;_IMAGE:214570 mixed
CB161552.1 Clone L17N670205n1-35-B02 liver 5' read
CB163361.1 Clone L17N670205n1-26-H12 liver 5' read A
AI668605.1 Clone IMAGE:161884 mammary gland 3' read
AI677905.1 Clone IMAGE:2330082 mixed 3' read A
AI733540.1 Clone IMAGE:161884 mammary gland 5' read
CB269613.1 adipose tissue 5' read P
AI820779.1 Clone IMAGE:161570 mammary gland 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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