> Serine palmitoyltransferase, long chain base subunit 1 (SPTLC1)
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UGID:141368     UniGene Hs.90458     Homo sapiens (human)   SPTLC1 Order cDNA clone, Links
Serine palmitoyltransferase, long chain base subunit 1 (SPTLC1)

Human protein-coding gene SPTLC1. Represented by 649 ESTs from 257 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 141368 - Hs.90458]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_006406.1 SPTLC1 gene product H. sapiens 100.0 472
XP_520127.4 PREDICTED: serine palmitoyltransferase 1-like P. troglodytes 100.0 339
XP_003912019.1 PREDICTED: serine palmitoyltransferase 1 P. anubis 99.8 472
NP_033295.2 Sptlc1 gene product M. musculus 95.3 472
NP_001084963.1 serine palmitoyltransferase, long chain base subunit 1 X. laevis 91.5 471
NP_001018307.1 sptlc1 gene product D. rerio 90.2 470
NP_610842.1 serine palmitoyltransferase subunit I, isoform A D. melanogaster 65.4 459
NP_001021978.1 Protein SPTL-1, isoform a C. elegans 60.5 453
NP_568005.1 serine palmitoyltransferase A. thaliana 50.3 441
XP_001695593.1 serine palmitoyltransferase C. reinhardtii 49.9 329
XP_957979.1 hypothetical protein NCU06870 N. crassa 47.2 252
NP_014025.1 serine C-palmitoyltransferase LCB1 S. cerevisiae 46.3 216
Other hits (2 of 54) [Show all]SpeciesId(%)Len(aa)
XP_001102219.2 PREDICTED: serine palmitoyltransferase 1 M. mulatta 99.5 377
XP_003483426.1 PREDICTED: serine palmitoyltransferase 1-like S. scrofa 97.7 472

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; intestine; testis; placenta; uncharacterized tissue; spleen; embryonic tissue; uterus; liver; eye; lung; prostate; adrenal gland; kidney; mixed; bladder; skin; ovary; pituitary gland; connective tissue; heart; stomach; esophagus; trachea; pancreas; vascular; muscle; bone marrow; mouth; thymus; thyroid; cervix; mammary gland; blood; lymph node; pharynx; bone; ascites; ganglia; nerve; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9q22.2
UniSTS entry: Chr 9 G19655
UniSTS entry: Chr 9 A001U11 [Map Viewer]
UniSTS entry: Chr 9 G17347
UniSTS entry: Chr 1 D10S275
UniSTS entry: Chr 1 D1S1425
UniSTS entry: Chr 1 G44365
UniSTS entry: Chr 1 D11S2921
UniSTS entry: D9S1973
UniSTS entry: Chr 1 RH26813
UniSTS entry: Chr 1 D11S2560
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

NM_178324.1 Homo sapiens serine palmitoyltransferase, long chain base subunit 1 (SPTLC1), transcript variant 2, mRNA PA
NM_006415.2 Homo sapiens serine palmitoyltransferase, long chain base subunit 1 (SPTLC1), transcript variant 1, mRNA P
BC068537.1 Homo sapiens serine palmitoyltransferase, long chain base subunit 1, mRNA (cDNA clone MGC:87384 IMAGE:5259635), complete cds PA
AB209757.1 Homo sapiens mRNA for serine palmitoyltransferase subunit 1 isoform a variant protein P
BC007085.1 Homo sapiens serine palmitoyltransferase, long chain base subunit 1, mRNA (cDNA clone IMAGE:4094854), complete cds PA
AK291546.1 Homo sapiens cDNA FLJ75707 complete cds, highly similar to Homo sapiens serine palmitoyltransferase, long chain base subunit 1 (SPTLC1), transcript variant 1, mRNA P
AK309775.1 Homo sapiens cDNA, FLJ99816 P
AK098344.1 Homo sapiens cDNA FLJ25478 fis, clone CBL03360 P
AK299153.1 Homo sapiens cDNA FLJ57569 complete cds, highly similar to Serine palmitoyltransferase 1 (EC 2.3.1.50) P
AF116613.1 Homo sapiens clone FLB3822 mRNA sequence
AF147304.1 Homo sapiens full length insert cDNA clone YA77H04 A
Y08685.1 H.sapiens mRNA for serine palmitoyltransferase, subunit I P

EST sequences (10 of 649) [Show all sequences]

R15433.1 Clone IMAGE:53381 brain 5' read P
AA973574.1 Clone IMAGE:1569304 lung 3' read A
AA987710.1 Clone IMAGE:1593411 kidney 3' read
AA902722.1 Clone IMAGE:1519454 uncharacterized tissue 3' read A
AI089675.1 Clone IMAGE:1686392 brain 3' read A
BX107634.1 Clone IMAGp998D215673_;_IMAGE:2290148 uterus A
R26887.1 Clone IMAGE:133401 placenta 3' read A
R27119.1 Clone IMAGE:133401 placenta 5' read
R28251.1 Clone IMAGE:133883 placenta 5' read
AI261605.1 Clone IMAGE:2028922 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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