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UGID:141355     UniGene Hs.90303     Homo sapiens (human)   TSC2
Tuberous sclerosis 2 (TSC2)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_000539.2 tuberous sclerosis 2 isoform 1 H. sapiens 100.0 1806
XP_523477.2 PREDICTED: tuberous sclerosis 2 P. troglodytes 99.8 1802
NP_035777.2 tuberous sclerosis 2 isoform 1 M. musculus 95.5 1784
XP_695912.3 PREDICTED: tuberous sclerosis 2, partial D. rerio 69.2 1065

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; thymus; testis; cervix; connective tissue; ovary; larynx; mammary gland; adrenal gland; embryonic tissue; skin; mixed; lung; lymph; eye; placenta; prostate; intestine; uncharacterized tissue; spleen; epididymis; blood; pancreas; adipose tissue; mouth; kidney; uterus; lymph node; thyroid; pineal gland; pituitary gland; muscle; stomach; bone marrow; trachea; ascites; nerve; bladder; bone; liver; parathyroid; heart
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p13.3
UniSTS entry: RH48126
UniSTS entry: Chr 16 STS-L48546
UniSTS entry: Chr 16 SHGC-30026
UniSTS entry: Chr 16 D8S1350E
UniSTS entry: Chr 16 (n/a)
UniSTS entry: (n/a)
UniSTS entry: Chr 2 D10S16
UniSTS entry: RH78697
UniSTS entry: Chr 16 D16S3394
UniSTS entry: Chr 16 GDB:378419
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

BC046929.1 Homo sapiens tuberous sclerosis 2, mRNA (cDNA clone IMAGE:3687567), partial cds PA
BX647816.1 Homo sapiens mRNA; cDNA DKFZp686N1252 (from clone DKFZp686N1252) PA
AK125096.1 Homo sapiens cDNA FLJ43106 fis, clone CTONG2016869, highly similar to Tuberin P
NM_000548.3 Homo sapiens tuberous sclerosis 2 (TSC2), transcript variant 1, mRNA PA
CR613640.1 full-length cDNA clone CS0DB005YA07 of Neuroblastoma Cot 10-normalized of Homo sapiens (human) P
CR601803.1 full-length cDNA clone CS0DI015YH15 of Placenta Cot 25-normalized of Homo sapiens (human) P
AB210000.1 Homo sapiens mRNA for SLC9A3R2 variant protein, partial cds, clone: eh00696 P
NM_001077183.1 Homo sapiens tuberous sclerosis 2 (TSC2), transcript variant 4, mRNA PA
BC150300.1 Homo sapiens tuberous sclerosis 2, mRNA (cDNA clone MGC:167048 IMAGE:8860381), complete cds PA
BC025364.1 Homo sapiens, Similar to tuberous sclerosis 2, clone IMAGE:3687776, mRNA, partial cds PA
NM_001114382.1 Homo sapiens tuberous sclerosis 2 (TSC2), transcript variant 5, mRNA PA
AK094152.1 Homo sapiens cDNA FLJ36833 fis, clone ASTRO2010819, highly similar to TUBERIN P
AK299343.1 Homo sapiens cDNA FLJ55876 complete cds, highly similar to Tuberin PA
AK295728.1 Homo sapiens cDNA FLJ59695 complete cds, highly similar to Tuberin P
AK295672.1 Homo sapiens cDNA FLJ59538 complete cds, highly similar to Tuberin PA
AK294548.1 Homo sapiens cDNA FLJ52486 complete cds, highly similar to Tuberin P
X75621.1 Homo sapiens TSC2 mRNA for tuberin P

EST sequences (10 of 575) [Show all sequences]

AA968962.1 Clone IMAGE:1574625 kidney 3' read PA
AI005181.1 Clone IMAGE:1632184 mammary gland 3' read PA
AI024801.1 Clone IMAGE:1639332 testis 3' read P
AI025207.1 Clone IMAGE:1639817 testis 3' read P
AI039971.1 Clone IMAGE:1663426 skin 3' read PA
AI041012.1 Clone IMAGE:1642550 testis 3' read PA
AI078136.1 Clone IMAGE:1676822 embryonic tissue 3' read P
AI088282.1 Clone IMAGE:1693697 heart 3' read PA
AI142773.1 Clone IMAGE:1634251 mixed 3' read
BX112945.1 Clone IMAGp998F08403_;_IMAGE:207367 mixed P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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