> 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC)
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UGID:141351     UniGene Hs.90280     Homo sapiens (human)   ATIC Order cDNA clone, Links
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC)

Human protein-coding gene ATIC. Represented by 947 ESTs from 361 cDNA libraries. Corresponds to reference sequence NM_004044.6. [UniGene 141351 - Hs.90280]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001150761.1 PREDICTED: bifunctional purine biosynthesis protein PURH isoform 10 P. troglodytes 100.0 591
NP_004035.2 ATIC gene product H. sapiens 100.0 591
NP_080471.2 Atic gene product M. musculus 93.9 591
NP_001076265.2 atic gene product D. rerio 83.7 589
NP_001090100.1 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase X. laevis 82.5 588
NP_651305.1 CG11089, isoform A D. melanogaster 76.6 589
NP_013839.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase ADE17 S. cerevisiae 68.0 586
XP_964054.1 bifunctional purine biosynthesis protein N. crassa 67.8 590
NP_741452.2 Protein C55F2.1, isoform b C. elegans 66.1 589
NP_001189681.1 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP A. thaliana 46.0 198
Other hits (2 of 55) [Show all]SpeciesId(%)Len(aa)
XP_003907966.1 PREDICTED: bifunctional purine biosynthesis protein PURH isoform 1 P. anubis 99.3 591
XP_002808069.1 PREDICTED: LOW QUALITY PROTEIN: bifunctional purine biosynthesis protein PURH-like M. mulatta 99.2 591

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; intestine; uncharacterized tissue; testis; skin; mixed; embryonic tissue; eye; placenta; liver; lymph; prostate; lung; kidney; muscle; uterus; stomach; pancreas; connective tissue; esophagus; pharynx; blood; mammary gland; spinal cord; bone marrow; ovary; lymph node; adrenal gland; bladder; spleen; pituitary gland; thymus; bone; tonsil; larynx; ascites; heart; cervix; ganglia; amniotic fluid; thyroid; vascular; adipose tissue; trachea; mouth; nerve; umbilical cord; ear
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q35
UniSTS entry: Chr 2 RH11837
UniSTS entry: Chr 2 SGC31824 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

NM_004044.6 Homo sapiens 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC), mRNA PA
BC008879.2 Homo sapiens 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase, mRNA (cDNA clone MGC:15334 IMAGE:4300570), complete cds PA
AK313066.1 Homo sapiens cDNA, FLJ93545, highly similar to Homo sapiens 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC), mRNA P
AB062403.1 Homo sapiens OK/SW-cl.86 mRNA for 5-aminoimidazole-4-carboxamide-1-bata-D-ribon ucleotid transformylase/inosinicase, complete cds PA
D89976.1 Homo sapiens mRNA for 5-aminoimidazole-4-carboxamide ribonucleotide transformylase, complete cds P

EST sequences (10 of 947) [Show all sequences]

AA866164.1 Clone IMAGE:1469437 uncharacterized tissue 3' read
AA984408.1 Clone IMAGE:1629931 brain 3' read PA
AI000072.1 Clone IMAGE:1608773 mammary gland 3' read PA
AA911092.1 Clone IMAGE:1519048 uncharacterized tissue 3' read PA
AI023728.1 Clone IMAGE:1654982 mixed 3' read PA
R20197.1 Clone IMAGE:34440 brain 5' read P
AI075185.1 Clone IMAGE:1673655 mixed 3' read PA
AI093346.1 Clone IMAGE:1695110 uterus 3' read PA
AI093922.1 Clone IMAGE:1687987 mixed 3' read P
AI093923.1 Clone IMAGE:1687989 mixed 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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