> Transketolase (TKT)
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UGID:141292     UniGene Hs.89643     Homo sapiens (human)   TKT Order cDNA clone, Links
Transketolase (TKT)

Human protein-coding gene TKT. Represented by 2851 ESTs from 523 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 141292 - Hs.89643]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001244957.1 TKT gene product H. sapiens 100.0 630
NP_001009097.1 TKT gene product P. troglodytes 100.0 622
XP_003894341.1 PREDICTED: transketolase isoform 3 P. anubis 99.8 630
NP_033414.1 transketolase M. musculus 98.4 622
NP_001083312.1 transketolase X. laevis 85.2 623
XP_685690.2 PREDICTED: transketolase-like D. rerio 79.5 624
NP_501878.1 Protein TKT-1 C. elegans 70.4 615
NP_649812.2 CG8036, isoform B D. melanogaster 68.1 623
Other hits (2 of 39) [Show all]SpeciesId(%)Len(aa)
XP_001492213.3 PREDICTED: transketolase E. caballus 98.1 575
NP_001106151.1 TKT gene product S. scrofa 97.9 622

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; blood; uncharacterized tissue; skin; lung; testis; embryonic tissue; placenta; intestine; eye; thymus; liver; kidney; mixed; cervix; mammary gland; uterus; pancreas; spleen; connective tissue; prostate; lymph; stomach; vascular; ovary; thyroid; bone marrow; trachea; ascites; bladder; adrenal gland; lymph node; esophagus; bone; heart; mouth; umbilical cord; salivary gland; muscle; tonsil; adipose tissue; nerve; ganglia; pituitary gland; amniotic fluid; pharynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3p14.3
UniSTS entry: Chr 3 WI-18916 [Map Viewer]
UniSTS entry: Chr 3 RH79674
UniSTS entry: Chr 3 MARC_13462-13463:1002299004:1
UniSTS entry: Chr 3 SHGC-57226
UniSTS entry: TKT
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

BX647248.1 Homo sapiens mRNA; cDNA DKFZp686B0599 (from clone DKFZp686B0599) PA
NM_001064.3 Homo sapiens transketolase (TKT), transcript variant 1, mRNA PA
AK223614.1 Homo sapiens mRNA for transketolase variant, clone: FCC133E07 PA
L12711.1 Homo sapiens transketolase (tk) mRNA, complete cds P
BC008615.1 Homo sapiens transketolase, mRNA (cDNA clone IMAGE:4156339), partial cds PA
U55017.1 Human transketolase (TKT) mRNA, complete cds PA
BC009970.2 Homo sapiens transketolase, mRNA (cDNA clone MGC:15349 IMAGE:4310396), complete cds PA
AK289454.1 Homo sapiens cDNA FLJ76204 complete cds, highly similar to Homo sapiens transketolase (Wernicke-Korsakoff syndrome) (TKT), mRNA P
AK309482.1 Homo sapiens cDNA, FLJ99523 P
BC024026.2 Homo sapiens transketolase, mRNA (cDNA clone IMAGE:2966643), partial cds PA
AK093667.1 Homo sapiens cDNA FLJ36348 fis, clone THYMU2007025, highly similar to TRANSKETOLASE (EC 2.2.1.1) PA
AK301231.1 Homo sapiens cDNA FLJ53217 complete cds, highly similar to Transketolase (EC 2.2.1.1) P
AK293438.1 Homo sapiens cDNA FLJ54957 complete cds, highly similar to Transketolase (EC 2.2.1.1) P
AK303191.1 Homo sapiens cDNA FLJ56274 complete cds, highly similar to Transketolase (EC 2.2.1.1) P
NM_001135055.2 Homo sapiens transketolase (TKT), transcript variant 2, mRNA PA
BC002433.2 Homo sapiens transketolase, mRNA (cDNA clone MGC:2211 IMAGE:3346980), complete cds PA
X67688.1 H.sapiens mRNA for transketolase PA
NM_001258028.1 Homo sapiens transketolase (TKT), transcript variant 3, mRNA PA
NR_047580.1 Homo sapiens transketolase (TKT), transcript variant 5, non-coding RNA PA

EST sequences (10 of 2851) [Show all sequences]

AA954833.1 Clone IMAGE:1574338 kidney 3' read P
AA962451.1 Clone IMAGE:1553586 kidney 3' read
AA946720.1 Clone IMAGE:1421052 intestine 3' read P
AI002354.1 Clone IMAGE:1593309 kidney 3' read P
AI056476.1 Clone IMAGE:1669514 brain 3' read P
AI074092.1 Clone IMAGE:1594273 intestine 3' read P
AI076541.1 Clone IMAGE:1674869 mixed 3' read P
AI143071.1 Clone IMAGE:1705588 heart 3' read A
AI143455.1 Clone IMAGE:1690684 mixed 3' read PA
BX117093.1 Clone IMAGp998B20176_;_IMAGE:42648 brain PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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