> Proteasome (prosome, macropain) subunit, beta type, 4 (PSMB4)
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UGID:141268     UniGene Hs.89545     Homo sapiens (human)   PSMB4
Proteasome (prosome, macropain) subunit, beta type, 4 (PSMB4)

Human protein-coding gene PSMB4. Represented by 1416 ESTs from 423 cDNA libraries. Corresponds to reference sequence NM_002796.2. [UniGene 141268 - Hs.89545]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001108305.1 PREDICTED: proteasome subunit beta type-4-like isoform 3 M. mulatta 100.0 263
NP_001162425.1 PSMB4 gene product P. anubis 100.0 263
XP_003949592.1 PREDICTED: proteasome subunit beta type-4 P. troglodytes 100.0 263
NP_002787.2 PSMB4 gene product H. sapiens 100.0 263
NP_032971.2 Psmb4 gene product M. musculus 98.9 263
NP_001017801.1 psmb4 gene product D. rerio 85.6 214
NP_001080890.1 proteasome subunit beta type-4 X. laevis 83.5 247
NP_176040.1 proteasome subunit beta type-4 A. thaliana 48.2 224
NP_116708.1 proteasome core particle subunit beta 7 S. cerevisiae 47.6 206
NP_649529.1 proteasome beta7 subunit, isoform A D. melanogaster 45.5 178
Other hits (2 of 52) [Show all]SpeciesId(%)Len(aa)
NP_001164776.1 PSMB4 gene product O. cuniculus 98.8 260
XP_533057.3 PREDICTED: proteasome subunit beta type-4 C. lupus familiaris 98.5 263

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: skin; brain; lung; placenta; eye; mixed; uterus; prostate; liver; embryonic tissue; pancreas; uncharacterized tissue; mammary gland; kidney; ovary; bone; lymph; intestine; ear; adrenal gland; ascites; bladder; cervix; amniotic fluid; thyroid; blood; testis; tonsil; stomach; epididymis; lymph node; mouth; heart; muscle; thymus; connective tissue; pituitary gland; vascular; spleen; parathyroid; salivary gland; pharynx; nerve; bone marrow; larynx; pineal gland; umbilical cord; esophagus; spinal cord
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q21
UniSTS entry: Chr 1 MARC_13789-13790:1025290513:1
UniSTS entry: Chr 1 stSG627163
UniSTS entry: Chr 1 G54029
UniSTS entry: Chr 1 REN33985
UniSTS entry: Chr 1 ECD10374
UniSTS entry: Chr 1 REN33988
UniSTS entry: Chr 1 REN33986
UniSTS entry: Chr 1 REN33987
UniSTS entry: Chr 1 REN33990
UniSTS entry: Chr 1 REN33984
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

BT006917.1 Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4 mRNA, complete cds P
NM_002796.2 Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4 (PSMB4), mRNA P
CR456820.1 Homo sapiens full open reading frame cDNA clone RZPDo834E0215D for gene PSMB4, proteasome (prosome, macropain) subunit, beta type, 4; complete cds, incl. stopcodon P
D26600.1 Homo sapiens mRNA for proteasome subunit HsN3, complete cds P
BC000331.1 Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4, mRNA (cDNA clone IMAGE:2822513) PA
BC008314.2 Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4, mRNA (cDNA clone IMAGE:3143023) PA
BC010098.2 Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4, mRNA (cDNA clone IMAGE:3505166) PA
BC010088.2 Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4, mRNA (cDNA clone IMAGE:2967687) PA
BC012168.2 Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4, mRNA (cDNA clone IMAGE:4640238) PA
BC011768.2 Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4, mRNA (cDNA clone IMAGE:3607881) PA
BC017451.2 Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4, mRNA (cDNA clone IMAGE:3543917) PA
BC017307.1 Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4, mRNA (cDNA clone IMAGE:5088267) PA
BC017486.2 Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4, mRNA (cDNA clone IMAGE:3536964) PA
AK313825.1 Homo sapiens cDNA, FLJ94446, highly similar to Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4 (PSMB4), mRNA P
AK294149.1 Homo sapiens cDNA FLJ56661 complete cds, highly similar to Proteasome subunit beta type 4 precursor (EC 3.4.25.1) P

EST sequences (10 of 1416) [Show all sequences]

AA903040.1 Clone IMAGE:1517480 uncharacterized tissue 3' read P
AA968500.1 Clone IMAGE:1574992 kidney 3' read PA
AA987252.1 Clone IMAGE:1604259 lung 3' read P
AA989583.1 Clone IMAGE:1576917 spleen 3' read A
AI001185.1 Clone IMAGE:1637764 mammary gland 3' read P
R17408.1 Clone IMAGE:30871 brain 5' read P
AI015012.1 Clone IMAGE:1618286 testis 3' read PA
AI028000.1 Clone IMAGE:1646128 parathyroid 3' read P
AI032324.1 Clone IMAGE:1644228 testis 3' read A
AI033883.1 Clone IMAGE:1646452 parathyroid 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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