> Fyn-related kinase (FRK)
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UGID:141245     UniGene Hs.89426     Homo sapiens (human)   FRK
Fyn-related kinase (FRK)

Human protein-coding gene FRK. Represented by 31 ESTs from 17 cDNA libraries. EST representation biased toward adult. Corresponds to reference sequence NM_002031.2. [UniGene 141245 - Hs.89426]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_002022.1 FRK gene product H. sapiens 100.0 504
NP_001153016.1 Frk gene product M. musculus 92.0 511
XP_695937.5 PREDICTED: tyrosine-protein kinase FRK-like isoform 4 D. rerio 69.7 455
NP_476849.1 Src oncogene at 42A, isoform A D. melanogaster 67.3 461
NP_493502.1 Protein SRC-2 C. elegans 56.7 443
NP_001079115.1 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog X. laevis 53.1 456
Other hits (2 of 42) [Show all]SpeciesId(%)Len(aa)
XP_518702.2 PREDICTED: tyrosine-protein kinase FRK isoform 2 P. troglodytes 99.4 504
XP_001112190.1 PREDICTED: tyrosine-protein kinase FRK isoform 2 M. mulatta 97.2 504

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; mammary gland; mouth; larynx; mixed; liver; bladder; placenta; thymus; prostate; ascites; connective tissue; pancreas
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6q21-q22.3
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

NM_002031.2 Homo sapiens fyn-related kinase (FRK), mRNA PA
U22322.1 Human nuclear tyrosine protein kinase Rak mRNA, complete cds P
BC012916.1 Homo sapiens fyn-related kinase, mRNA (cDNA clone MGC:21276 IMAGE:4515877), complete cds PA
AK313314.1 Homo sapiens cDNA, FLJ93829, highly similar to Homo sapiens fyn-related kinase (FRK), mRNA P
AK302264.1 Homo sapiens cDNA FLJ59784 complete cds, highly similar to Tyrosine-protein kinase FRK (EC 2.7.10.2) P
U00803.1 Human SRC-like tyrosine kinase (FRK) mRNA, complete cds PA

EST sequences (10 of 31) [Show all sequences]

BX279578.1 Clone IMAGp998D1810432_;_IMAGE:4525793 bladder P
BX494753.1 Clone DKFZp779H2115 liver 5' read
CV025080.1 mixed 5' read P
AV659861.2 Clone GLCGBE10 liver 3' read
DR004414.1 Clone TC118859 placenta 5' read P
BF088269.1 larynx
DA440126.1 Clone CTONG2008594 mouth 5' read
DA434699.1 Clone CTONG2001201 mouth 5' read
DB003908.1 Clone TBAES2006501 mammary gland 5' read
DB032924.1 Clone TESTI2017536 testis 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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