> Autophagy related 4A, cysteine peptidase (ATG4A)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:132395     UniGene Hs.8763     Homo sapiens (human)   ATG4A Order cDNA clone, Links
Autophagy related 4A, cysteine peptidase (ATG4A)

Human protein-coding gene ATG4A. Represented by 173 ESTs from 111 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 132395 - Hs.8763]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001233457.1 ATG4A gene product P. troglodytes 100.0 397
NP_443168.2 ATG4A gene product H. sapiens 100.0 397
XP_001097251.1 PREDICTED: cysteine protease ATG4A isoform 6 M. mulatta 99.8 397
XP_003918174.1 PREDICTED: cysteine protease ATG4A isoform 1 P. anubis 99.8 397
NP_777364.3 Atg4a gene product M. musculus 96.0 395
NP_001106295.1 APG4A protein X. laevis 83.8 394
NP_001019605.1 atg4a gene product D. rerio 79.1 374
NP_493375.2 Protein ATG-4.1, isoform a C. elegans 56.6 263
NP_608563.1 Autophagy-specific gene 4, isoform A D. melanogaster 54.0 276
Other hits (2 of 36) [Show all]SpeciesId(%)Len(aa)
XP_002720229.1 PREDICTED: autophagy-related cysteine endopeptidase 2 O. cuniculus 98.5 397
XP_001490718.3 PREDICTED: cysteine protease ATG4A E. caballus 98.2 397

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; pancreas; uncharacterized tissue; cervix; lung; pharynx; placenta; mammary gland; muscle; mixed; liver; lymph; vascular; blood; ovary; spleen; bone marrow; eye; bladder; tonsil; connective tissue; pituitary gland; esophagus; thymus; trachea; kidney; uterus; testis; intestine; prostate; mouth; skin; bone; adipose tissue; embryonic tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: Xq22.1-q22.3
UniSTS entry: Chr X WI-18722 [Map Viewer]
UniSTS entry: Chr X DXS8284 [Map Viewer]
UniSTS entry: Chr X G20822
UniSTS entry: Chr X A006H40 [Map Viewer]
UniSTS entry: ATG4A
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BC041862.1 Homo sapiens ATG4 autophagy related 4 homolog A (S. cerevisiae), mRNA (cDNA clone MGC:43691 IMAGE:5271295), complete cds PA
AJ504651.1 Homo sapiens mRNA for autophagin-2 (AUTL2 gene) P
NM_178270.2 Homo sapiens autophagy related 4A, cysteine peptidase (ATG4A), transcript variant 2, mRNA PA
BC061696.1 Homo sapiens ATG4 autophagy related 4 homolog A (S. cerevisiae), mRNA (cDNA clone MGC:62085 IMAGE:4594225), complete cds PA
AJ320509.1 Homo sapiens mRNA for putative autophagy-related cysteine endopeptidase 2, short splice variant (AUTL2 gene) P
AJ320508.1 Homo sapiens mRNA for putative autophagy-related cysteine endopeptidase 2 (AUTL2 gene) P
NM_052936.3 Homo sapiens autophagy related 4A, cysteine peptidase (ATG4A), transcript variant 1, mRNA PA
AK054927.1 Homo sapiens cDNA FLJ30365 fis, clone BRACE2007784 P
AB066214.1 Homo sapiens mRNA for Apg4A, complete cds P
AK314429.1 Homo sapiens cDNA, FLJ95220, highly similar to Homo sapiens AUT-like 2, cysteine endopeptidase (S. cerevisiae) (AUTL2), mRNA P
AK293533.1 Homo sapiens cDNA FLJ60428 complete cds, highly similar to Homo sapiens ATG4 autophagy related 4 homolog A, transcript variant 2, mRNA P

EST sequences (10 of 173) [Show all sequences]

AI024115.1 Clone IMAGE:1643575 testis 3' read A
AI042121.1 Clone IMAGE:1665681 skin 3' read A
AI127937.1 Clone IMAGE:1711336 uterus 3' read P
BX089876.1 Clone IMAGp998A241202_;_IMAGE:503711 uterus P
AI188815.1 Clone IMAGE:1723980 placenta 3' read A
CB126756.1 Clone L5HLK1s1-25-E02 liver 5' read P
AA897607.1 Clone IMAGE:1504384 mixed 3' read A
AA905599.1 Clone IMAGE:1506626 mixed 3' read
AI375174.1 Clone IMAGE:2063426 mixed 3' read A
AI382598.1 Clone IMAGE:2020528 uncharacterized tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help