Harakiri, BCL2 interacting protein (contains only BH3 domain) (HRK)

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UGID:141036 UniGene Hs.87247 Homo sapiens (human) HRK

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Harakiri, BCL2 interacting protein (contains only BH3 domain) (HRK)

Human protein-coding gene HRK. Represented by 13 ESTs from 11 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 141036 - Hs.87247]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_003907266.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: activator of apoptosis harakiri	P. anubis	100.0	90
XP_001145194.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: activator of apoptosis harakiri	P. troglodytes	100.0	90
NP_003797.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	HRK gene product	H. sapiens	100.0	90
Other hits (2 of 5) [Show all]		Species	Id(%)	Len(aa)
NP_001178170.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	HRK gene product	B. taurus	98.9	90
XP_002719855.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: harakiri	O. cuniculus	98.9	90

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources.
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	uncharacterized tissue; mixed; placenta; thyroid; lymph node; testis; brain

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	12
	Map position:	12q24.22

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (4)

NM_003806.2	Homo sapiens harakiri, BCL2 interacting protein (contains only BH3 domain) (HRK), transcript variant 1, mRNA	PA
D83699.1	Homo sapiens DP5 mRNA, 3'UTR partial sequence	A
U76376.1	Homo sapiens activator of apoptosis Hrk (HRK) mRNA, complete cds	PA
NR_073189.1	Homo sapiens harakiri, BCL2 interacting protein (contains only BH3 domain) (HRK), transcript variant 2, non-coding RNA	PA

EST sequences (13)

AA906802.1	Clone IMAGE:1519582	uncharacterized tissue	3' read
BX118100.1	Clone IMAGp998L201889_;_IMAGE:767779	mixed		A
AI083676.1	Clone IMAGE:1671299	uncharacterized tissue	3' read
BX351422.2	Clone CS0DI012YG14	placenta	3' read	A
BE165899.1		thyroid
BE247231.1	Clone TCBAP3841	lymph node
CR741487.1	Clone IMAGp998K124602_;_IMAGE:1879043	uncharacterized tissue	5' read
BE674890.1	Clone IMAGE:3293060	uncharacterized tissue	3' read
BF093413.1		testis
DA610452.1	Clone IMR322008325	brain	5' read
BF510077.1	Clone IMAGE:3086902	uncharacterized tissue	3' read
C00709.2		uncharacterized tissue
AA418229.1	Clone IMAGE:767779	mixed	5' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria