> Growth factor receptor-bound protein 7 (GRB7)
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UGID:140982     UniGene Hs.86859     Homo sapiens (human)   GRB7 Order cDNA clone, Links
Growth factor receptor-bound protein 7 (GRB7)

Human protein-coding gene GRB7. Represented by 207 ESTs from 116 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 140982 - Hs.86859]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001171807.2 PREDICTED: growth factor receptor-bound protein 7 isoform 3 P. troglodytes 100.0 554
NP_001229371.1 GRB7 gene product H. sapiens 100.0 554
XP_001091728.1 PREDICTED: growth factor receptor-bound protein 7-like isoform 2 M. mulatta 99.6 531
XP_003912989.1 PREDICTED: growth factor receptor-bound protein 7 isoform 1 P. anubis 99.6 531
NP_034476.1 Grb7 gene product M. musculus 93.5 534
NP_001004287.1 grb10a gene product D. rerio 59.6 574
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
XP_548141.2 PREDICTED: growth factor receptor-bound protein 7 isoform 1 C. lupus familiaris 96.4 529
XP_001501087.2 PREDICTED: LOW QUALITY PROTEIN: growth factor receptor-bound protein 7 E. caballus 96.4 548

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; intestine; brain; lung; cervix; kidney; testis; mouth; mixed; prostate; mammary gland; uterus; uncharacterized tissue; ovary; pancreas; liver; stomach; lymph node; embryonic tissue; trachea; esophagus; larynx; adipose tissue; bladder; thymus; skin; eye; ascites; pharynx; connective tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17q12
UniSTS entry: Chr 17 WI-9366
UniSTS entry: Chr 17 STS-D43772
UniSTS entry: Chr 17 GRB7_4323
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

AB008789.1 Homo sapiens mRNA for grb7 protein, complete cds P
AB008790.1 Homo sapiens mRNA for Grb7V protein, complete cds P
BT006686.1 Homo sapiens growth factor receptor-bound protein 7 mRNA, complete cds P
AK125544.1 Homo sapiens cDNA FLJ43556 fis, clone PROST2018511, highly similar to Growth factor receptor-bound protein 7 P
NM_005310.3 Homo sapiens growth factor receptor-bound protein 7 (GRB7), transcript variant 1, mRNA PA
D43772.1 Homo sapiens mRNA for GRB-7 SH2 domain protein, complete cds P
AK222870.1 Homo sapiens mRNA for growth factor receptor-bound protein 7 variant, clone: HEP15586 P
AK222849.1 Homo sapiens mRNA for growth factor receptor-bound protein 7 variant, clone: HEP10521 P
NM_001030002.2 Homo sapiens growth factor receptor-bound protein 7 (GRB7), transcript variant 2, mRNA PA
AK027729.1 Homo sapiens cDNA FLJ14823 fis, clone OVARC1000649, highly similar to Growth factor receptor-bound protein 7 P
BC006535.2 Homo sapiens growth factor receptor-bound protein 7, mRNA (cDNA clone MGC:1444 IMAGE:2824302), complete cds PA
AK290115.1 Homo sapiens cDNA FLJ75489 complete cds, highly similar to Homo sapiens growth factor receptor-bound protein 7, transcript variant 2, mRNA P
AK314368.1 Homo sapiens cDNA, FLJ95136, highly similar to Homo sapiens growth factor receptor-bound protein 7 (GRB7), mRNA P
AK294620.1 Homo sapiens cDNA FLJ57923 complete cds, highly similar to Growth factor receptor-bound protein 7 P
D87513.1 Homo sapiens mRNA for Grb7 protein, partial cds P
NM_001242443.1 Homo sapiens growth factor receptor-bound protein 7 (GRB7), transcript variant 3, mRNA PA
NM_001242442.1 Homo sapiens growth factor receptor-bound protein 7 (GRB7), transcript variant 4, mRNA PA

EST sequences (10 of 207) [Show all sequences]

R21206.1 Clone IMAGE:130323 placenta 5' read
AI087865.1 Clone IMAGE:1651193 mixed 3' read A
R22820.1 Clone IMAGE:130323 placenta 3' read A
AI126258.1 Clone IMAGE:1713519 placenta 3' read A
BX094412.1 Clone IMAGp998L04179_;_IMAGE:130323 placenta P
CB137059.1 Clone L6ChoCK0-25-G11 liver 5' read P
AI336922.1 Clone IMAGE:2009453 uncharacterized tissue 3' read A
AI361784.1 Clone IMAGE:2021967 uncharacterized tissue 3' read
AI473829.1 Clone IMAGE:2155547 intestine 3' read A
AI691143.1 Clone IMAGE:2276831 uterus 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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