> Myeloid leukemia factor 1 (MLF1)
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UGID:140846     UniGene Hs.85195     Homo sapiens (human)   MLF1
Myeloid leukemia factor 1 (MLF1)

Human protein-coding gene MLF1. Represented by 318 ESTs from 102 cDNA libraries. Corresponds to 6 reference sequences (different isoforms). [UniGene 140846 - Hs.85195]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001182361.1 MLF1 gene product H. sapiens 100.0 298
XP_516842.2 PREDICTED: myeloid leukemia factor 1 isoform 9 P. troglodytes 99.6 267
NP_001034632.1 Mlf1 gene product M. musculus 85.1 281
NP_001088844.1 myeloid leukemia factor 1 X. laevis 66.5 244
XP_003200041.1 PREDICTED: myeloid leukemia factor 1 D. rerio 59.6 269
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
XP_003894947.1 PREDICTED: myeloid leukemia factor 1 isoform 2 P. anubis 96.1 279
XP_001102054.1 PREDICTED: myeloid leukemia factor 1-like isoform 9 M. mulatta 95.9 266

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; muscle; lung; mixed; uncharacterized tissue; bladder; heart; placenta; skin; embryonic tissue; pharynx; ovary; kidney; mammary gland; intestine; prostate; nerve; pineal gland; bone marrow; larynx; connective tissue; uterus; eye; ascites; bone; liver; parathyroid; mouth; salivary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3q25.1
UniSTS entry: Chr 3 STS-L49054 [Map Viewer]
UniSTS entry: Chr 3 SHGC-35682 [Map Viewer]
UniSTS entry: Chr 3 RH102628
UniSTS entry: Chr 1 D10S16
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

BX647666.1 Homo sapiens mRNA; cDNA DKFZp313B1621 (from clone DKFZp313B1621) PA
BX641078.1 Homo sapiens mRNA; cDNA DKFZp686A04129 (from clone DKFZp686A04129) A
BC095437.1 Homo sapiens cDNA clone IMAGE:30720866, containing frame-shift errors PA
L49054.1 Homo sapiens t(3;5)(q25.1;p34) fusion gene NPM-MLF1 mRNA, complete cds PA
AY848702.1 Homo sapiens myeloid leukemia factor 1 variant 3 (MLF1) mRNA, complete cds, alternatively spliced PA
AY848701.1 Homo sapiens myeloid leukemia factor 1 variant 2 (MLF1) mRNA, complete cds, alternatively spliced PA
AY848700.1 Homo sapiens myeloid leukemia factor 1 variant 1 (MLF1) mRNA, complete cds, alternatively spliced PA
NM_022443.4 Homo sapiens myeloid leukemia factor 1 (MLF1), transcript variant 1, mRNA PA
BC007045.1 Homo sapiens myeloid leukemia factor 1, mRNA (cDNA clone MGC:12449 IMAGE:3996145), complete cds PA
AK056948.1 Homo sapiens cDNA FLJ32386 fis, clone SKMUS1000118, highly similar to Homo sapiens t(3;5)(q25.1;p34) fusion gene NPM-MLF1 mRNA P
AK315402.1 Homo sapiens cDNA, FLJ96451, highly similar to Homo sapiens myeloid leukemia factor 1 (MLF1), mRNA P
AK096889.1 Homo sapiens cDNA FLJ39570 fis, clone SKMUS2001850, highly similar to Homo sapiens t(3;5)(q25.1;p34) fusion gene NPM-MLF1 mRNA P
NM_001130157.2 Homo sapiens myeloid leukemia factor 1 (MLF1), transcript variant 2, mRNA PA
NM_001130156.2 Homo sapiens myeloid leukemia factor 1 (MLF1), transcript variant 3, mRNA PA
AK297488.1 Homo sapiens cDNA FLJ52995 complete cds, highly similar to Myeloid leukemia factor 1 PA
NM_001195434.1 Homo sapiens myeloid leukemia factor 1 (MLF1), transcript variant 6, mRNA P
NM_001195433.1 Homo sapiens myeloid leukemia factor 1 (MLF1), transcript variant 5, mRNA P
NM_001195432.1 Homo sapiens myeloid leukemia factor 1 (MLF1), transcript variant 4, mRNA P

EST sequences (10 of 318) [Show all sequences]

AA974317.1 Clone IMAGE:1585959 uncharacterized tissue 3' read
AI014921.1 Clone IMAGE:1623266 embryonic tissue 3' read
AI015466.1 Clone IMAGE:1641154 testis 3' read
AI015525.1 Clone IMAGE:1636068 kidney 3' read P
AA837018.1 Clone IMAGE:1439313 lung
AI140690.1 Clone IMAGE:1738178 testis 3' read
AI141092.1 Clone IMAGE:1739764 lung 3' read P
BX113820.1 Clone IMAGp998D191824_;_IMAGE:742626 testis P
AI185669.1 Clone IMAGE:1743863 lung 3' read P
AI193725.1 Clone IMAGE:1744656 lung 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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