Keratin 20 (KRT20)

Restricted Expression:

intestine [show more like this]

colorectal tumor [show more like this]

adult [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

intestine; stomach; mixed; muscle; kidney; brain

NCBI

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Finding cDNAs

UGID:140831 UniGene Hs.84905 Homo sapiens (human) KRT20

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Keratin 20 (KRT20)

Human protein-coding gene KRT20. Represented by 112 ESTs from 46 cDNA libraries. EST representation biased toward intestine; colorectal tumor; adult. Corresponds to reference sequence NM_019010.2. [UniGene 140831 - Hs.84905]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_061883.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	KRT20 gene product	H. sapiens	100.0	423
XP_001168931.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: keratin, type I cytoskeletal 20 isoform 3	P. troglodytes	99.8	423
NP_075745.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Krt20 gene product	M. musculus	82.4	430
NP_001002383.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	zgc:92061 gene product	D. rerio	56.6	419
NP_001082432.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	keratin, type I cytoskeletal 47 kDa	X. laevis	52.0	452
Other hits (2 of 20) [Show all]		Species	Id(%)	Len(aa)
XP_003913054.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: keratin, type I cytoskeletal 20	P. anubis	96.9	423
XP_001101772.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: keratin, type I cytoskeletal 20	M. mulatta	96.5	423

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	17
Map position:	17q21.2
UniSTS entry:	Chr 17	RH18130
UniSTS entry:	Chr 17	D17S1996	[Map Viewer]

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (4)

NM_019010.2	Homo sapiens keratin 20 (KRT20), mRNA	PA
AK312744.1	Homo sapiens cDNA, FLJ93153, highly similar to Homo sapiens keratin 20 (KRT20), mRNA	P
BC031559.1	Homo sapiens keratin 20, mRNA (cDNA clone MGC:35423 IMAGE:5189289), complete cds	PA
X73502.1	H. Sapiens mRNA for cytokeratin 20	PA

EST sequences (10 of 112) [Show all sequences]

BX098834.1	Clone IMAGp998E052187_;_IMAGE:882028	intestine		PA
AI720245.1	Clone IMAGE:2335411	intestine	3' read	A
AI732166.1	Clone IMAGE:882028	intestine	3' read	A
AI732381.1	Clone IMAGE:936345	intestine	3' read	A
AI821179.1	Clone IMAGE:882028	intestine	5' read	P
BX483738.1	Clone DKFZp686K24238	muscle	5' read	P
AW362720.1		intestine
AW363792.1		intestine
AW842862.1		intestine
AW842995.1		intestine

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria