> Fatty acid synthase (FASN)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:140714     UniGene Hs.83190     Homo sapiens (human)   FASN Order cDNA clone, Links
Fatty acid synthase (FASN)

Human protein-coding gene FASN. Represented by 1422 ESTs from 258 cDNA libraries. Corresponds to reference sequence NM_004104.4. [UniGene 140714 - Hs.83190]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_004095.4 FASN gene product H. sapiens 100.0 2510
NP_032014.3 Fasn gene product M. musculus 87.1 2503
XP_001923643.1 PREDICTED: fatty acid synthase D. rerio 71.4 2510
NP_492417.2 Protein FASN-1 C. elegans 56.0 2569
NP_647613.1 v(2)k05816, isoform A D. melanogaster 53.5 2376
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_511758.2 PREDICTED: fatty acid synthase isoform 2 P. troglodytes 99.3 2501
XP_003913649.1 PREDICTED: fatty acid synthase P. anubis 95.9 2509

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: prostate; skin; brain; lung; uncharacterized tissue; eye; mammary gland; embryonic tissue; placenta; liver; intestine; ovary; mixed; pancreas; uterus; muscle; lymph; testis; lymph node; cervix; bladder; kidney; larynx; spleen; ascites; nerve; bone; adipose tissue; blood; adrenal gland; pituitary gland; connective tissue; stomach; salivary gland; epididymis; heart; vascular; pharynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17q25
UniSTS entry: Chr 17 D17S1256
UniSTS entry: Chr 17 FASN_7242
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

NM_004104.4 Homo sapiens fatty acid synthase (FASN), mRNA PA
BC063242.1 Homo sapiens fatty acid synthase, mRNA (cDNA clone MGC:60044 IMAGE:6172538), complete cds PA
AY451392.1 Homo sapiens fatty acid synthase mRNA, complete cds P
U29344.1 Human breast carcinoma fatty acid synthase mRNA, complete cds P
AB209988.1 Homo sapiens mRNA for FASN variant protein, partial cds, clone: ae00014 P
BC007909.1 Homo sapiens fatty acid synthase, mRNA (cDNA clone IMAGE:4299348), complete cds PA
BC007305.2 Homo sapiens fatty acid synthase, mRNA (cDNA clone IMAGE:3352118), partial cds PA
BC007267.1 Homo sapiens, clone IMAGE:3138929, mRNA, partial cds PA
BC014634.2 Homo sapiens fatty acid synthase, mRNA (cDNA clone IMAGE:3535581), partial cds PA
BC014631.2 Homo sapiens fatty acid synthase, mRNA (cDNA clone IMAGE:3351370), partial cds PA
BC021544.2 Homo sapiens fatty acid synthase, mRNA (cDNA clone IMAGE:3355480), partial cds PA
S80437.1 fatty acid synthase {3' region} [human, breast and HepG2 cells, mRNA Partial, 2237 nt] PA

EST sequences (10 of 1422) [Show all sequences]

AA995057.1 Clone IMAGE:1631559 mammary gland 3' read A
AA911112.1 Clone IMAGE:1519063 uncharacterized tissue 3' read A
R18484.1 Clone IMAGE:30252 brain 5' read
AI037943.1 Clone IMAGE:1660017 embryonic tissue 3' read A
AI039428.1 Clone IMAGE:1658269 embryonic tissue 3' read
AI073336.1 Clone IMAGE:1632330 mammary gland 3' read A
AI129371.1 Clone IMAGE:1711488 uterus 3' read A
AI143390.1 Clone IMAGE:1690302 mixed 3' read A
AI249810.1 Clone IMAGE:2000765 lymph node 3' read A
CB145064.1 Clone L11SNU354s1-5-F10 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help