> Midkine (neurite growth-promoting factor 2) (MDK)
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UGID:140584     UniGene Hs.82045     Homo sapiens (human)   MDK Order cDNA clone, Links
Midkine (neurite growth-promoting factor 2) (MDK)

Human protein-coding gene MDK. Represented by 559 ESTs from 190 cDNA libraries. EST representation biased toward embryoid body. Corresponds to 7 reference sequences (different isoforms). [UniGene 140584 - Hs.82045]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001257479.1 MDK gene product H. sapiens 100.0 142
NP_001012336.1 Mdk gene product M. musculus 89.3 139
NP_001081356.1 midkine-A precursor X. laevis 67.6 141
NP_571145.1 mdka gene product D. rerio 67.6 145
Other hits (2 of 15) [Show all]SpeciesId(%)Len(aa)
XP_001112400.1 PREDICTED: midkine isoform 1 M. mulatta 99.4 165
XP_003910020.1 PREDICTED: midkine P. anubis 98.8 171

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: embryoid body [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: embryonic tissue; brain; pancreas; skin; adrenal gland; epididymis; stomach; ovary; uterus; testis; uncharacterized tissue; bone; lung; mammary gland; intestine; blood; prostate; muscle; mixed; eye; kidney; umbilical cord; pharynx; heart; placenta; larynx; lymph node; liver; connective tissue; parathyroid; pituitary gland; cervix; ascites; spleen; thyroid; salivary gland; pineal gland; mouth; ear
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p11.2
UniSTS entry: Chr 11 D11S4595
UniSTS entry: MARC_2215-2216:991932659:1
UniSTS entry: Chr 11 MDK
UniSTS entry: MDK
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

AK130889.1 Homo sapiens cDNA FLJ27379 fis, clone UBA07284, highly similar to Midkine precursor P
NM_002391.4 Homo sapiens midkine (neurite growth-promoting factor 2) (MDK), transcript variant 3, mRNA PA
NM_001012333.2 Homo sapiens midkine (neurite growth-promoting factor 2) (MDK), transcript variant 2, mRNA PA
NM_001012334.2 Homo sapiens midkine (neurite growth-promoting factor 2) (MDK), transcript variant 1, mRNA PA
M69148.1 Human midkine mRNA, complete cds P
DQ323890.1 Homo sapiens mutant truncated midkine C (MDK) mRNA, complete cds A
DQ323889.1 Homo sapiens mutant truncated midkine B (MDK) mRNA, complete cds A
DQ323888.1 Homo sapiens mutant truncated midkine A (MDK) mRNA, complete cds PA
BC011704.2 Homo sapiens midkine (neurite growth-promoting factor 2), mRNA (cDNA clone MGC:19557 IMAGE:3609004), complete cds PA
AK308210.1 Homo sapiens cDNA, FLJ98158 P
AK309963.1 Homo sapiens cDNA, FLJ17005 PA
X55110.1 Human mRNA for neurite outgrowth-promoting protein PA
NR_073039.1 Homo sapiens midkine (neurite growth-promoting factor 2) (MDK), transcript variant 7, non-coding RNA PA
NM_001270551.1 Homo sapiens midkine (neurite growth-promoting factor 2) (MDK), transcript variant 5, mRNA PA
NM_001270552.1 Homo sapiens midkine (neurite growth-promoting factor 2) (MDK), transcript variant 6, mRNA PA
NM_001270550.1 Homo sapiens midkine (neurite growth-promoting factor 2) (MDK), transcript variant 4, mRNA PA

EST sequences (10 of 559) [Show all sequences]

AA968896.1 Clone IMAGE:1574594 kidney 3' read A
AA928381.1 Clone IMAGE:1553144 uncharacterized tissue 3' read A
AA947686.1 Clone IMAGE:1584920 lung 3' read A
AI051519.1 Clone IMAGE:1659100 embryonic tissue 3' read A
AI127036.1 Clone IMAGE:1708021 heart 3' read A
AI185816.1 Clone IMAGE:1742372 lung 3' read A
CB109442.1 Clone L4SNU368-10-C08 liver 5' read
CB111177.1 Clone L4SNU368-16-D05 liver 5' read P
CB120838.1 Clone C1SNU17-1-G02 cervix 5' read P
AA885582.1 Clone IMAGE:1499891 lung 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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