> Transforming growth factor, beta receptor II (70/80kDa) (TGFBR2)
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UGID:140579     UniGene Hs.82028     Homo sapiens (human)   TGFBR2 Links
Transforming growth factor, beta receptor II (70/80kDa) (TGFBR2)

Human protein-coding gene TGFBR2. Represented by 493 ESTs from 220 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 140579 - Hs.82028]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_516343.2 PREDICTED: TGF-beta receptor type-2 isoform 3 P. troglodytes 100.0 591
NP_001020018.1 TGFBR2 gene product H. sapiens 100.0 591
NP_033397.3 Tgfbr2 gene product M. musculus 95.4 591
NP_878275.2 tgfbr2 gene product D. rerio 80.3 542
NP_001084061.1 activin receptor type-2A precursor X. laevis 47.7 300
NP_731926.1 punt, isoform A D. melanogaster 46.3 164
Other hits (2 of 36) [Show all]SpeciesId(%)Len(aa)
XP_001095987.1 PREDICTED: TGF-beta receptor type-2 isoform 3 M. mulatta 99.3 566
XP_003895258.1 PREDICTED: TGF-beta receptor type-2 isoform 2 P. anubis 99.0 591

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mixed; brain; uterus; placenta; intestine; kidney; spleen; bladder; connective tissue; uncharacterized tissue; esophagus; lung; pancreas; mammary gland; pituitary gland; skin; eye; amniotic fluid; embryonic tissue; cervix; liver; ear; blood; muscle; bone marrow; adipose tissue; mouth; adrenal gland; stomach; bone; testis; vascular; trachea; ascites; lymph; ganglia; heart; lymph node; prostate; thyroid; ovary; parathyroid; thymus; umbilical cord
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3p22
UniSTS entry: Chr 3 A006H18
UniSTS entry: Chr 3 G32353
UniSTS entry: Chr 3 SHGC-32684 [Map Viewer]
UniSTS entry: Chr 3 RH47188 [Map Viewer]
UniSTS entry: Tgfbr2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

BX648313.1 Homo sapiens mRNA; cDNA DKFZp686C10170 (from clone DKFZp686C10170) A
NM_003242.5 Homo sapiens transforming growth factor, beta receptor II (70/80kDa) (TGFBR2), transcript variant 2, mRNA P
AJ786388.1 Homo sapiens partial mRNA for transforming growth factor beta receptor type IIC, (Tbeta RIIC gene), alternative splicing
NM_001024847.2 Homo sapiens transforming growth factor, beta receptor II (70/80kDa) (TGFBR2), transcript variant 1, mRNA P
M85079.1 Human TGF-beta type II receptor mRNA, complete cds P
AK314102.1 Homo sapiens cDNA, FLJ94789, highly similar to Homo sapiens transforming growth factor, beta receptor II(70/80kDa) (TGFBR2), mRNA P
AK300383.1 Homo sapiens cDNA FLJ53920 complete cds, highly similar to TGF-beta receptor type-2 precursor (EC 2.7.11.30) P
AK304404.1 Homo sapiens cDNA FLJ51462 complete cds, highly similar to TGF-beta receptor type-2 precursor (EC 2.7.11.30) P
D28131.1 Homo sapiens mRNA for TGF-beta receptor type IIB, partial cds P
BC040499.1 Homo sapiens transforming growth factor, beta receptor II (70/80kDa), mRNA (cDNA clone IMAGE:5287742) PA

EST sequences (10 of 493) [Show all sequences]

AA973715.1 Clone IMAGE:1585998 uncharacterized tissue 3' read A
AA902586.1 Clone IMAGE:1502686 kidney 3' read A
AI025745.1 Clone IMAGE:1646526 parathyroid 3' read
AI074706.1 Clone IMAGE:1662925 mixed 3' read
AI094550.1 Clone IMAGE:1634918 mixed 3' read A
AI094965.1 Clone IMAGE:1686308 brain 3' read A
R23693.1 Clone IMAGE:131708 placenta 5' read
AI146295.1 Clone IMAGE:1707073 heart 3' read A
AI147568.1 Clone IMAGE:1696926 uterus 3' read A
AI148760.1 Clone IMAGE:1714891 placenta 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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