> Pim-1 oncogene (PIM1)
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UGID:140520     UniGene Hs.81170     Homo sapiens (human)   PIM1 Order cDNA clone, Links
Pim-1 oncogene (PIM1)

Human protein-coding gene PIM1. Represented by 398 ESTs from 183 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 140520 - Hs.81170]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001230115.1 PIM1 gene product H. sapiens 100.0 403
XP_003311330.1 PREDICTED: serine/threonine-protein kinase pim-1, partial P. troglodytes 99.8 457
NP_001139649.1 proto-oncogene serine/threonine-protein kinase pim-1 C. lupus familiaris 99.7 312
XP_001500275.1 PREDICTED: proto-oncogene serine/threonine-protein kinase pim-1 E. caballus 99.7 312
NP_032868.2 Pim1 gene product M. musculus 97.4 312
NP_001070859.1 zgc:153997 gene product D. rerio 82.5 315
NP_001090165.1 pim-3 oncogene X. laevis 78.7 314
NP_497696.2 Protein PRK-2 C. elegans 50.0 270
Other hits (2 of 24) [Show all]SpeciesId(%)Len(aa)
XP_001113117.1 PREDICTED: proto-oncogene serine/threonine-protein kinase pim-1 M. mulatta 99.3 460
XP_003897598.1 PREDICTED: serine/threonine-protein kinase pim-1, partial P. anubis 99.3 460

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mixed; uncharacterized tissue; skin; bone marrow; heart; umbilical cord; brain; embryonic tissue; mouth; blood; placenta; cervix; liver; testis; kidney; connective tissue; ovary; adrenal gland; nerve; spleen; pharynx; parathyroid; eye; lymph node; esophagus; amniotic fluid; thymus; uterus; muscle; intestine; pancreas; lung; stomach; vascular; trachea; larynx; lymph; ascites; mammary gland; salivary gland; bone; prostate; thyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p21.2
UniSTS entry: Chr 6 RH46728
UniSTS entry: Chr 6 D6S2043
UniSTS entry: Chr 6 G10642
UniSTS entry: Chr 6 D6S1832 [Map Viewer]
UniSTS entry: Chr 6 Pim1
UniSTS entry: Chr 6 MARC_14741-14742:1010683927:1
UniSTS entry: Chr 14 PMC97568P1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

M54915.1 Human h-pim-1 protein (h-pim-1) mRNA, complete cds P
NM_002648.3 Homo sapiens pim-1 oncogene (PIM1), transcript variant 1, mRNA PA
M24779.1 Homo sapiens protein kinase-related oncogene (PIM1) mRNA, complete cds P
DQ022562.1 Homo sapiens pim-1 kinase 44 kDa isoform mRNA, complete cds PA
M16750.1 Human pim-1 oncogene mRNA, complete cds P
BC020224.1 Homo sapiens pim-1 oncogene, mRNA (cDNA clone MGC:31919 IMAGE:4591723), complete cds PA
AK309347.1 Homo sapiens cDNA, FLJ99388 P
AK301314.1 Homo sapiens cDNA FLJ50255 complete cds P
AK301158.1 Homo sapiens cDNA FLJ61426 complete cds, highly similar to Proto-oncogene serine/threonine-protein kinase Pim-1 (EC 2.7.11.1) P
NM_001243186.1 Homo sapiens pim-1 oncogene (PIM1), transcript variant 1, mRNA PA

EST sequences (10 of 398) [Show all sequences]

AA995939.1 Clone IMAGE:1635820 kidney 3' read
AI022194.1 Clone IMAGE:1654315 mixed 3' read A
AI027463.1 Clone IMAGE:1646024 parathyroid 3' read A
AA928975.1 Clone IMAGE:1567400 lung 3' read A
AI095209.1 Clone IMAGE:1672425 uncharacterized tissue 3' read P
AA864935.1 Clone IMAGE:1469627 uncharacterized tissue 3' read A
AI126985.1 Clone IMAGE:1707976 heart 3' read
AI141790.1 Clone IMAGE:1690759 mixed 3' read A
AI188827.1 Clone IMAGE:1723985 placenta 3' read A
AI215611.1 Clone IMAGE:1845036 mixed 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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