> Antigen identified by monoclonal antibody Ki-67 (MKI67)
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UGID:140506     UniGene Hs.80976     Homo sapiens (human)   MKI67 Links
Antigen identified by monoclonal antibody Ki-67 (MKI67)

Human protein-coding gene MKI67. Represented by 544 ESTs from 237 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 140506 - Hs.80976]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_002408.3 MKI67 gene product H. sapiens 100.0 3255
NP_001074586.2 Mki67 gene product M. musculus 56.4 2954
Other hits (2 of 10) [Show all]SpeciesId(%)Len(aa)
XP_508147.2 PREDICTED: antigen KI-67 isoform 2 P. troglodytes 98.1 3256
XP_003904463.1 PREDICTED: antigen KI-67 P. anubis 90.8 3263

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mixed; uncharacterized tissue; intestine; lymph node; liver; uterus; blood; embryonic tissue; ovary; lung; placenta; esophagus; thymus; kidney; mammary gland; testis; thyroid; vascular; brain; cervix; bone marrow; eye; prostate; ascites; connective tissue; bone; muscle; mouth; lymph; heart; stomach; skin; bladder; pharynx; spleen; adrenal gland; pancreas; larynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q26.2
UniSTS entry: Chr 10 RH1579
UniSTS entry: Chr 10 STS-R96656 [Map Viewer]
UniSTS entry: Chr 10 D10S2184
UniSTS entry: Chr 10 SHGC-52534 [Map Viewer]
UniSTS entry: Chr 10 D10S1202
UniSTS entry: Chr 10 MKI67_7831
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_002417.4 Homo sapiens antigen identified by monoclonal antibody Ki-67 (MKI67), transcript variant 1, mRNA PA
AJ567757.1 Homo sapiens partial mRNA for KI67 Antigen (MKI67 gene), variant lacking exons 3-12
AJ567756.1 Homo sapiens partial mRNA for KI67 Antigen (MKI67 gene), variant lacking exons 3,4 and 7 P
AK299254.1 Homo sapiens cDNA FLJ56929 complete cds, highly similar to Antigen KI-67 P
X65550.1 H.sapiens mki67a mRNA (long type) for antigen of monoclonal antibody Ki-67 PA
X65551.1 H.sapiens mki67a mRNA (short type) for antigen of monoclonal antibody Ki-67 PA
NM_001145966.1 Homo sapiens antigen identified by monoclonal antibody Ki-67 (MKI67), transcript variant 2, mRNA PA

EST sequences (10 of 544) [Show all sequences]

AI002455.1 Clone IMAGE:1592901 kidney 3' read P
AI003885.1 Clone IMAGE:1621808 testis 3' read
AI014749.1 Clone IMAGE:1611154 uncharacterized tissue 3' read
AI032126.1 Clone IMAGE:1611261 uncharacterized tissue 3' read
AI052209.1 Clone IMAGE:1675308 mixed 3' read PA
AI088763.1 Clone IMAGE:1687370 brain 3' read A
AI130853.1 Clone IMAGE:1709551 heart 3' read A
AI140054.1 Clone IMAGE:1693709 heart 3' read A
BX118911.1 Clone IMAGp998G2380_;_IMAGE:108718 mixed
CB146989.1 Clone L16HLK3-31-B09 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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