> Betaine--homocysteine S-methyltransferase (BHMT)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:140493     UniGene Hs.80756     Homo sapiens (human)   BHMT Order cDNA clone, Links
Betaine--homocysteine S-methyltransferase (BHMT)

Human protein-coding gene BHMT. Represented by 471 ESTs from 42 cDNA libraries. EST representation biased toward liver tumor; fetus. Corresponds to reference sequence NM_001713.2. [UniGene 140493 - Hs.80756]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001704.2 BHMT gene product H. sapiens 100.0 405
XP_003899907.1 PREDICTED: betaine--homocysteine S-methyltransferase 1 P. anubis 99.8 405
XP_517686.3 PREDICTED: betaine--homocysteine S-methyltransferase 1 isoform 2 P. troglodytes 99.8 405
NP_057877.1 Bhmt gene product M. musculus 96.3 405
NP_001088416.1 betaine--homocysteine S-methyltransferase 1 X. laevis 88.1 402
NP_001012498.1 bhmt gene product D. rerio 82.2 399
Other hits (2 of 25) [Show all]SpeciesId(%)Len(aa)
XP_001104072.2 PREDICTED: betaine--homocysteine S-methyltransferase 1 M. mulatta 98.6 421
NP_001186971.1 BHMT gene product S. scrofa 97.3 405

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: liver tumor [show more like this]
fetus [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: kidney; liver; eye; mixed; brain; mammary gland; intestine; uncharacterized tissue; embryonic tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5q14.1
UniSTS entry: Chr 5 RH16250 [Map Viewer]
UniSTS entry: Chr 5 RH35961 [Map Viewer]
UniSTS entry: Chr 5 SGC33609 [Map Viewer]
UniSTS entry: Chr 5 RH91498
UniSTS entry: Chr 5 RH80672
UniSTS entry: btcn45788
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

NM_001713.2 Homo sapiens betaine--homocysteine S-methyltransferase (BHMT), mRNA PA
BC012616.1 Homo sapiens betaine-homocysteine methyltransferase, mRNA (cDNA clone MGC:13645 IMAGE:4045543), complete cds PA
AK315224.1 Homo sapiens cDNA, FLJ96222, highly similar to Homo sapiens betaine-homocysteine methyltransferase (BHMT), mRNA P
AK298308.1 Homo sapiens cDNA FLJ54604 complete cds, highly similar to Betaine--homocysteine S-methyltransferase (EC 2.1.1.5) P
AK303780.1 Homo sapiens cDNA FLJ50349 complete cds, moderately similar to Betaine--homocysteine S-methyltransferase (EC 2.1.1.5) P
U50929.1 Human betaine:homocysteine methyltransferase mRNA, complete cds PA

EST sequences (10 of 471) [Show all sequences]

AA983313.1 Clone IMAGE:1590392 kidney 3' read A
AA995526.1 Clone IMAGE:1606646 kidney 3' read A
BX118188.1 Clone IMAGp998L17657_;_IMAGE:294688 mixed
CB148997.1 Clone L17N670205-1-G05 liver 5' read
CB157595.1 Clone L17N670205n1-11-G08 liver 5' read
CB163550.1 Clone L17N670205n1-32-F03 liver 5' read
CB163799.1 Clone L17N670205n1-46-H03 liver 5' read
CB142728.1 Clone L7N800102-13-C12 liver 5' read P
AI244216.1 Clone IMAGE:1866342 kidney 3' read P
AI244533.1 Clone IMAGE:1868945 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help