> Growth arrest and DNA-damage-inducible, alpha (GADD45A)
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UGID:140462     UniGene Hs.80409     Homo sapiens (human)   GADD45A Order cDNA clone, Links
Growth arrest and DNA-damage-inducible, alpha (GADD45A)

Human protein-coding gene GADD45A. Represented by 220 ESTs from 123 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 140462 - Hs.80409]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001095413.1 PREDICTED: growth arrest and DNA damage-inducible protein GADD45 alpha isoform 2 M. mulatta 100.0 164
XP_003892082.1 PREDICTED: growth arrest and DNA damage-inducible protein GADD45 alpha P. anubis 100.0 164
XP_513476.2 PREDICTED: growth arrest and DNA damage-inducible protein GADD45 alpha isoform 2 P. troglodytes 100.0 164
NP_001915.1 GADD45A gene product H. sapiens 100.0 164
NP_001029419.1 GADD45A gene product B. taurus 100.0 164
XP_004002113.1 PREDICTED: growth arrest and DNA damage-inducible protein GADD45 alpha isoform 1 O. aries 100.0 164
NP_031862.1 Gadd45a gene product M. musculus 99.4 164
NP_001079537.1 growth arrest and DNA-damage-inducible, alpha X. laevis 75.2 156
NP_001002216.1 gadd45ab gene product D. rerio 73.1 155
Other hits (2 of 18) [Show all]SpeciesId(%)Len(aa)
XP_002715979.1 PREDICTED: growth arrest and DNA-damage-inducible, alpha O. cuniculus 99.4 164
NP_001038064.1 growth arrest and DNA damage-inducible protein GADD45 alpha S. scrofa 98.2 164

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; kidney; mixed; lung; uncharacterized tissue; uterus; embryonic tissue; eye; cervix; placenta; pancreas; intestine; liver; lymph; umbilical cord; prostate; testis; pharynx; vascular; lymph node; thymus; skin; mammary gland; blood; parathyroid; ovary; bone; connective tissue; bladder; stomach; muscle; thyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p31.2
UniSTS entry: Chr 1 SHGC-74965
UniSTS entry: Chr 1 D1S3318
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

M60974.1 Human growth arrest and DNA-damage-inducible protein (gadd45) mRNA, complete cds P
NM_001924.3 Homo sapiens growth arrest and DNA-damage-inducible, alpha (GADD45A), transcript variant 1, mRNA PA
DQ008445.1 Homo sapiens growth arrest and DNA-damage-inducible 45 alpha (GADD45A) mRNA, complete cds, alternatively spliced P
BC011757.2 Homo sapiens growth arrest and DNA-damage-inducible, alpha, mRNA (cDNA clone MGC:19584 IMAGE:3530326), complete cds PA
EF581092.1 Homo sapiens growth arrest and DNA-damage-inducible 45 alpha (GADD45A) mRNA, complete cds, alternatively spliced
EF614238.1 Homo sapiens growth arrest and DNA-damage-inducible 45 alpha (GADD45A) mRNA, complete sequence, alternatively spliced
AK314991.1 Homo sapiens cDNA, FLJ95917, Homo sapiens growth arrest and DNA-damage-inducible, alpha(GADD45A), mRNA P
NM_001199742.1 Homo sapiens growth arrest and DNA-damage-inducible, alpha (GADD45A), transcript variant 3, mRNA A
NM_001199741.1 Homo sapiens growth arrest and DNA-damage-inducible, alpha (GADD45A), transcript variant 2, mRNA PA

EST sequences (10 of 220) [Show all sequences]

AA962726.1 Clone IMAGE:1573323 kidney 3' read
AA992456.1 Clone IMAGE:1602788 lung 3' read A
AA999865.1 Clone IMAGE:1636383 kidney 3' read A
AI023067.1 Clone IMAGE:1651710 skin 3' read A
T05919.1 Clone HFBDI61 brain
AI129510.1 Clone IMAGE:1711522 uterus 3' read A
CB045463.1 Clone IMAGE:3218393 intestine 3' read A
CB045464.1 Clone IMAGE:3218393 intestine 5' read
BX090426.1 Clone IMAGp998P14697_;_IMAGE:310141 skin P
AI263481.1 Clone IMAGE:1855797 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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