Replication protein A2, 32kDa (RPA2)

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UGID:140397 UniGene Hs.79411 Homo sapiens (human) RPA2

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Replication protein A2, 32kDa (RPA2)

Human protein-coding gene RPA2. Represented by 511 ESTs from 259 cDNA libraries. Corresponds to reference sequence NM_002946.3. [UniGene 140397 - Hs.79411]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_003891479.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: replication protein A 32 kDa subunit	P. anubis	100.0	269
NP_002937.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	RPA2 gene product	H. sapiens	100.0	269
XP_003307967.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: replication protein A 32 kDa subunit isoform 1	P. troglodytes	100.0	268
XP_002802309.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: replication protein A 32 kDa subunit-like isoform 2	M. mulatta	99.6	269
NP_035414.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Rpa2 gene product	M. musculus	91.8	269
NP_001085393.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	replication protein A2, 32kDa	X. laevis	76.8	275
NP_571786.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	rpa2 gene product	D. rerio	63.5	271
Other hits (2 of 18) [Show all]		Species	Id(%)	Len(aa)
NP_001231871.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	replication protein A 32 kDa subunit	S. scrofa	96.3	269
NP_001039449.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	RPA2 gene product	B. taurus	95.2	269

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; testis; uncharacterized tissue; mammary gland; lung; vascular; placenta; pharynx; ovary; muscle; pineal gland; eye; blood; connective tissue; parathyroid; bone; mouth; skin; tonsil; larynx; lymph; intestine; embryonic tissue; prostate; uterus; mixed; spinal cord; kidney; bladder; pancreas; liver; heart; bone marrow; stomach; adrenal gland; thyroid; salivary gland; cervix; ascites; lymph node; thymus; spleen; nerve; ear; ganglia

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	1
Map position:	1p35
UniSTS entry:	Chr 10	G30996
UniSTS entry:	Chr 1	SHGC-30251	[Map Viewer]
UniSTS entry:	Chr 1	RH68976
UniSTS entry:	Chr 1	AL034207
UniSTS entry:	Chr 1	SHGC-124

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

J05249.1	Human replication protein A 32-kDa subunit mRNA, complete cds	P
NM_002946.3	Homo sapiens replication protein A2, 32kDa (RPA2), mRNA	PA
CR450348.1	Homo sapiens full open reading frame cDNA clone RZPDo834G092D for gene RPA2, replication protein A2, 32kDa; complete cds; without stopcodon	P
BC001630.1	Homo sapiens replication protein A2, 32kDa, mRNA (cDNA clone MGC:2229 IMAGE:3538351), complete cds	PA
BC012157.1	Homo sapiens replication protein A2, 32kDa, mRNA (cDNA clone MGC:20385 IMAGE:4563651), complete cds	PA
BC021257.2	Homo sapiens replication protein A2, 32kDa, mRNA (cDNA clone MGC:29683 IMAGE:4111194), complete cds	PA
AK312956.1	Homo sapiens cDNA, FLJ93412, highly similar to Homo sapiens replication protein A2, 32kDa (RPA2), mRNA	P
AK300691.1	Homo sapiens cDNA FLJ57152 complete cds, highly similar to Replication protein A 32 kDa subunit	P
AK298759.1	Homo sapiens cDNA FLJ61154 complete cds, highly similar to Replication protein A 32 kDa subunit	P

EST sequences (10 of 511) [Show all sequences]

AA961209.1	Clone IMAGE:1569837	lung	3' read	P
AA926824.1	Clone IMAGE:1486491	mouth	3' read
AA996246.1	Clone IMAGE:1605696	kidney	3' read	P
AI016125.1	Clone IMAGE:1618707	testis	3' read
AI040401.1	Clone IMAGE:1646383	parathyroid	3' read
AI149442.1	Clone IMAGE:1715185	placenta	3' read
CB145745.1	Clone L16HLK3-28-B12	liver	5' read	P
CB113002.1	Clone L6ChoCK0-8-B05	liver	5' read	P
CB155053.1	Clone B2N807043-32-B10	brain	5' read	P
CB151829.1	Clone C1SNU17-24-B07	cervix	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria