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UGID:140287     UniGene Hs.78944     Homo sapiens (human)   RGS2
Regulator of G-protein signaling 2, 24kDa (RGS2)

Human protein-coding gene RGS2. Represented by 423 ESTs from 177 cDNA libraries. Corresponds to reference sequence NM_002923.3. [UniGene 140287 - Hs.78944]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001112788.1 PREDICTED: regulator of G-protein signaling 2-like M. mulatta 100.0 210
XP_003893424.1 PREDICTED: regulator of G-protein signaling 2 P. anubis 100.0 210
XP_001166601.1 PREDICTED: regulator of G-protein signaling 2 isoform 1 P. troglodytes 100.0 210
NP_002914.1 RGS2 gene product H. sapiens 100.0 210
NP_033087.2 Rgs2 gene product M. musculus 98.1 210
NP_001088514.1 regulator of G-protein signaling 2, 24kDa X. laevis 77.2 214
NP_001003629.1 rgs3a gene product D. rerio 54.7 170
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
XP_545701.2 PREDICTED: regulator of G-protein signaling 2 C. lupus familiaris 99.0 200
NP_445905.1 Rgs2 gene product R. norvegicus 98.6 210

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: blood; uncharacterized tissue; brain; eye; pancreas; lung; uterus; kidney; prostate; mixed; placenta; intestine; mammary gland; pharynx; embryonic tissue; heart; spleen; pituitary gland; mouth; bladder; amniotic fluid; liver; bone marrow; nerve; esophagus; thymus; skin; ascites; connective tissue; stomach; testis; ovary; adipose tissue; muscle; bone; lymph node; thyroid; vascular; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q31
UniSTS entry: Chr 1 G54115
UniSTS entry: Chr 1 RH69011 [Map Viewer]
UniSTS entry: Chr 1 SHGC-76063 [Map Viewer]
UniSTS entry: Chr 1 D1S2392 [Map Viewer]
UniSTS entry: Chr 1 RH104484
UniSTS entry: Chr 1 PMC229255P4
UniSTS entry: Chr 1 GDB:683288
UniSTS entry: RGS2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

BC042755.1 Homo sapiens regulator of G-protein signaling 2, 24kDa, mRNA (cDNA clone IMAGE:4830785), complete cds A
BC044742.1 Homo sapiens regulator of G-protein signaling 2, 24kDa, mRNA (cDNA clone IMAGE:4829698) A
BT007065.1 Homo sapiens regulator of G-protein signalling 2, 24kDa mRNA, complete cds P
NM_002923.3 Homo sapiens regulator of G-protein signaling 2, 24kDa (RGS2), mRNA PA
CR457410.1 Homo sapiens full open reading frame cDNA clone RZPDo834H0910D for gene RGS2, regulator of G-protein signalling 2, 24kDa; complete cds, incl. stopcodon P
AY971351.1 Homo sapiens cell growth-inhibiting protein 31 mRNA, complete cds P
BC007049.1 Homo sapiens regulator of G-protein signaling 2, 24kDa, mRNA (cDNA clone MGC:12460 IMAGE:3681138), complete cds PA
AK313668.1 Homo sapiens cDNA, FLJ94250, Homo sapiens regulator of G-protein signalling 2, 24kDa (RGS2),mRNA P
AF493926.1 Homo sapiens regulator of G protein signalling 2 (RGS2) mRNA, complete cds P
L13463.1 Human helix-loop-helix basic phosphoprotein (G0S8) mRNA, complete cds P

EST sequences (10 of 423) [Show all sequences]

AA975385.1 Clone IMAGE:1556048 uncharacterized tissue 3' read A
AA834091.1 Clone IMAGE:1422252 kidney
AA922770.1 Clone IMAGE:1551777 uncharacterized tissue 3' read A
AI090227.1 Clone IMAGE:1697069 uterus 3' read
AI126225.1 Clone IMAGE:1736409 testis 3' read A
R23120.1 Clone IMAGE:130964 placenta 5' read
R23121.1 Clone IMAGE:130964 placenta 3' read A
AI139398.1 Clone IMAGE:1710996 uterus 3' read A
AI140249.1 Clone IMAGE:1739591 lung 3' read A
AI141220.1 Clone IMAGE:1739687 lung 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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