> Phosphoglycerate kinase 1 (PGK1)
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UGID:140251     UniGene Hs.78771     Homo sapiens (human)   PGK1
Phosphoglycerate kinase 1 (PGK1)

Human protein-coding gene PGK1. Represented by 4384 ESTs from 639 cDNA libraries. Corresponds to reference sequence NM_000291.3. [UniGene 140251 - Hs.78771]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001100787.1 PREDICTED: phosphoglycerate kinase 1 isoform 4 M. mulatta 100.0 416
XP_003917963.1 PREDICTED: phosphoglycerate kinase 1 P. anubis 100.0 416
NP_001129210.1 PGK1 gene product P. troglodytes 100.0 416
NP_000282.1 PGK1 gene product H. sapiens 100.0 416
NP_032854.2 Pgk1 gene product M. musculus 99.5 416
XP_002709046.1 PREDICTED: phosphoglycerate kinase 1 O. cuniculus 99.5 416
NP_998552.1 pgk1 gene product D. rerio 90.7 416
NP_001086928.1 phosphoglycerate kinase 1 X. laevis 90.4 416
NP_491245.1 Protein PGK-1 C. elegans 78.7 414
NP_476676.1 phosphoglycerate kinase, isoform A D. melanogaster 76.1 414
XP_962430.1 hypothetical protein NCU07914 N. crassa 76.0 416
NP_009938.2 phosphoglycerate kinase S. cerevisiae 72.5 414
XP_001699523.1 phosphoglycerate kinase C. reinhardtii 54.1 394
NP_178073.1 phosphoglycerate kinase A. thaliana 51.6 393
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
NP_445743.2 Pgk1 gene product R. norvegicus 99.3 416
NP_001029471.1 PGK1 gene product B. taurus 98.3 416

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; skin; liver; placenta; intestine; lung; kidney; uterus; heart; testis; embryonic tissue; blood; eye; ovary; cervix; mixed; connective tissue; ascites; muscle; prostate; stomach; mammary gland; thymus; esophagus; vascular; pancreas; bone marrow; spleen; lymph node; adrenal gland; thyroid; bone; umbilical cord; bladder; lymph; mouth; tonsil; trachea; pharynx; salivary gland; parathyroid; pituitary gland; larynx; adipose tissue; ganglia; pineal gland; nerve; epididymis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: Xq13.3
UniSTS entry: Chr X DXS7497 [Map Viewer]
UniSTS entry: Chr X DXS6983E [Map Viewer]
UniSTS entry: Chr X RH79992
UniSTS entry: Chr X RH36157 [Map Viewer]
UniSTS entry: Chr X RH10979 [Map Viewer]
UniSTS entry: Chr X WI-19211 [Map Viewer]
UniSTS entry: Chr X GDB:181567
UniSTS entry: Chr X STS-AA069778
UniSTS entry: AA892797
UniSTS entry: Chr X RH122374
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (22)

NM_000291.3 Homo sapiens phosphoglycerate kinase 1 (PGK1), mRNA PA
CR456716.1 Homo sapiens full open reading frame cDNA clone RZPDo834G123D for gene PGK1, phosphoglycerate kinase 1; complete cds, incl. stopcodon P
AY423725.1 Homo sapiens migration-inducing gene 10 protein mRNA, complete cds P
AY954501.1 Homo sapiens antigen MLAA-50 mRNA sequence A
AY954500.1 Homo sapiens antigen MMSA-10 mRNA sequence A
L00160.2 Homo sapiens phosphoglycerate kinase (PGK1) mRNA, partial cds. P
BC103752.1 Homo sapiens phosphoglycerate kinase 1, mRNA (cDNA clone MGC:117307 IMAGE:6526214), complete cds PA
BC104837.1 Homo sapiens phosphoglycerate kinase 1, mRNA (cDNA clone MGC:132497 IMAGE:8143840), complete cds P
BC113568.1 Homo sapiens phosphoglycerate kinase 1, mRNA (cDNA clone MGC:142128 IMAGE:8322620), complete cds P
AK291081.1 Homo sapiens cDNA FLJ78442 complete cds, highly similar to Homo sapiens phosphoglycerate kinase 1 (PGK1), mRNA P
S81916.1 phosphoglycerate kinase {alternatively spliced} [human, phosphoglycerate kinase deficient patient with episodes of muscl, mRNA Partial Mutant, 307 nt]
AK310756.1 Homo sapiens cDNA, FLJ17798 P
AK312280.1 Homo sapiens cDNA, FLJ92579, Homo sapiens phosphoglycerate kinase 1 (PGK1), mRNA P
AB062432.1 Homo sapiens OK/SW-cl.110 mRNA for phosphoglycerete kinase 1, complete cds PA
AK301632.1 Homo sapiens cDNA FLJ61438 complete cds, moderately similar to Phosphoglycerate kinase 1 (EC 2.7.2.3) P
AK298855.1 Homo sapiens cDNA FLJ51743 complete cds, highly similar to Phosphoglycerate kinase 1 (EC 2.7.2.3) P
AK303848.1 Homo sapiens cDNA FLJ53125 complete cds, highly similar to Phosphoglycerate kinase 1 (EC 2.7.2.3) P
AK295182.1 Homo sapiens cDNA FLJ52413 complete cds, highly similar to Phosphoglycerate kinase 1 (EC 2.7.2.3) P
AK295014.1 Homo sapiens cDNA FLJ53770 complete cds, highly similar to Phosphoglycerate kinase 1 (EC 2.7.2.3) P
BC023234.1 Homo sapiens phosphoglycerate kinase 1, mRNA (cDNA clone MGC:8947 IMAGE:3917985), complete cds PA
AK301740.1 Homo sapiens cDNA FLJ52414 complete cds, highly similar to Phosphoglycerate kinase 1 (EC 2.7.2.3) P
V00572.1 Human mRNA encoding phosphoglycerate kinase P

EST sequences (10 of 4384) [Show all sequences]

AA975187.1 Clone IMAGE:1555408 kidney 3' read A
AA975594.1 Clone IMAGE:1588905 kidney 3' read A
AA999785.1 Clone IMAGE:1606896 kidney 3' read
AI000724.1 Clone IMAGE:1636958 kidney 3' read A
AA834201.1 Clone IMAGE:1421195 kidney
AA834208.1 Clone IMAGE:1421222 kidney
AA922073.1 Clone IMAGE:1457238 intestine 3' read A
AI017381.1 Clone IMAGE:1635296 kidney 3' read A
AI037987.1 Clone IMAGE:1663871 skin 3' read A
R20131.1 Clone IMAGE:32551 brain 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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