> Thimet oligopeptidase 1 (THOP1)
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UGID:140250     UniGene Hs.78769     Homo sapiens (human)   THOP1 Order cDNA clone, Links
Thimet oligopeptidase 1 (THOP1)

Human protein-coding gene THOP1. Represented by 350 ESTs from 146 cDNA libraries. Corresponds to reference sequence NM_003249.3. [UniGene 140250 - Hs.78769]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003240.1 THOP1 gene product H. sapiens 100.0 688
NP_073144.3 Thop1 gene product M. musculus 93.2 686
NP_001002355.1 zgc:92139 gene product D. rerio 82.0 667
NP_001081384.1 thimet oligopeptidase 1 X. laevis 79.1 659
Other hits (2 of 38) [Show all]SpeciesId(%)Len(aa)
XP_003914681.1 PREDICTED: thimet oligopeptidase P. anubis 98.5 686
XP_001117760.2 PREDICTED: thimet oligopeptidase M. mulatta 94.7 748

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; placenta; lung; embryonic tissue; prostate; uterus; eye; ovary; connective tissue; mammary gland; bone marrow; skin; pharynx; lymph; adrenal gland; bladder; cervix; liver; ascites; mixed; intestine; lymph node; pancreas; tonsil; kidney; blood; stomach; larynx; ganglia; bone; muscle; heart; adipose tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.3
UniSTS entry: Chr 19 WI-14088 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

NM_003249.3 Homo sapiens thimet oligopeptidase 1 (THOP1), mRNA PA
BC067281.1 Homo sapiens thimet oligopeptidase 1, mRNA (cDNA clone IMAGE:6183983), with apparent retained intron PA
Z50115.1 H.sapiens mRNA for thimet oligopeptidase (metalloproteinase) P
U29366.1 Human thimet oligopeptidase (THOP1) mRNA, complete cds P
BC000135.2 Homo sapiens thimet oligopeptidase 1, mRNA (cDNA clone MGC:5271 IMAGE:2900551), complete cds PA
BC002391.2 Homo sapiens thimet oligopeptidase 1, mRNA (cDNA clone MGC:8357 IMAGE:2819803), complete cds PA
BC000583.2 Homo sapiens thimet oligopeptidase 1, mRNA (cDNA clone IMAGE:3163074), partial cds PA
BC013878.2 Homo sapiens thimet oligopeptidase 1, mRNA (cDNA clone MGC:10587 IMAGE:3690133), complete cds PA
BC150150.1 Homo sapiens cDNA clone IMAGE:40134244 P
AK093392.1 Homo sapiens cDNA FLJ36073 fis, clone TESTI2019697, highly similar to THIMET OLIGOPEPTIDASE (EC 3.4.24.15) P
AK300552.1 Homo sapiens cDNA FLJ56247 complete cds, highly similar to Thimet oligopeptidase (EC 3.4.24.15) P

EST sequences (10 of 350) [Show all sequences]

AI159972.1 Clone IMAGE:1706468 heart 3' read A
AI174502.1 Clone IMAGE:1701346 kidney 3' read A
AI184664.1 Clone IMAGE:1740199 lung 3' read A
AI394029.1 Clone IMAGE:2108495 uncharacterized tissue 3' read PA
AJ230807.1 Clone PS14D9 uncharacterized tissue 3' read
AI611701.1 Clone IMAGE:2263930 uterus 3' read A
R43175.1 Clone IMAGE:32751 brain 3' read A
AI695886.1 Clone IMAGE:2238237 uncharacterized tissue 3' read A
AI739282.1 Clone IMAGE:2390511 intestine 3' read A
AI765138.1 Clone IMAGE:2393520 intestine 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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