> Gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) (GGH)
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UGID:140237     UniGene Hs.78619     Homo sapiens (human)   GGH
Gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) (GGH)

Human protein-coding gene GGH. Represented by 277 ESTs from 133 cDNA libraries. Corresponds to reference sequence NM_003878.2. [UniGene 140237 - Hs.78619]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001159345.1 PREDICTED: gamma-glutamyl hydrolase isoform 1 P. troglodytes 100.0 317
NP_003869.1 GGH gene product H. sapiens 100.0 317
NP_034411.2 Ggh gene product M. musculus 77.0 316
NP_001086160.1 gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) precursor X. laevis 64.8 309
NP_001104645.1 zgc:171566 gene product D. rerio 59.1 312
Other hits (2 of 27) [Show all]SpeciesId(%)Len(aa)
XP_001091897.1 PREDICTED: gamma-glutamyl hydrolase M. mulatta 97.8 317
XP_003902852.1 PREDICTED: gamma-glutamyl hydrolase P. anubis 97.8 317

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; liver; uncharacterized tissue; kidney; mixed; vascular; skin; bone; intestine; spleen; placenta; uterus; eye; embryonic tissue; lung; adrenal gland; pancreas; heart; lymph; bone marrow; prostate; ascites; stomach; mammary gland; cervix; mouth; blood; connective tissue; esophagus; lymph node; ovary; muscle
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8q12.3
UniSTS entry: Chr 8 SHGC-36870 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (4)

NM_003878.2 Homo sapiens gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) (GGH), mRNA PA
AK290450.1 Homo sapiens cDNA FLJ76254 complete cds, highly similar to Homo sapiens gamma-glutamyl hydrolase (GGH), mRNA PA
BC025025.1 Homo sapiens gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase), mRNA (cDNA clone MGC:9649 IMAGE:3924620), complete cds PA
U55206.1 Homo sapiens human gamma-glutamyl hydrolase (hGH) mRNA, complete cds PA

EST sequences (10 of 277) [Show all sequences]

AA886895.1 Clone IMAGE:1493341 kidney 3' read PA
AI024523.1 Clone IMAGE:1631395 mammary gland 3' read PA
AA948379.1 Clone IMAGE:1560272 intestine 3' read PA
AI051617.1 Clone IMAGE:1674151 mixed 3' read PA
AI097260.1 Clone IMAGE:1704481 brain 3' read A
CB045441.1 Clone IMAGE:3218345 intestine 3' read PA
CB045442.1 Clone IMAGE:3218345 intestine 5' read P
BX091681.1 Clone IMAGp998B06273_;_IMAGE:46481 brain P
AI190829.1 Clone IMAGE:1732925 heart 3' read PA
AI205775.1 Clone IMAGE:1836903 testis 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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