> Natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) (NPR2)
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UGID:140224     UniGene Hs.78518     Homo sapiens (human)   NPR2 Links
Natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) (NPR2)

Human protein-coding gene NPR2. Represented by 134 ESTs from 74 cDNA libraries. Corresponds to reference sequence NM_003995.3. [UniGene 140224 - Hs.78518]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003911569.1 PREDICTED: atrial natriuretic peptide receptor 2 P. anubis 100.0 1046
NP_003986.2 NPR2 gene product H. sapiens 100.0 1046
XP_001085221.1 PREDICTED: atrial natriuretic peptide receptor 2 isoform 2 M. mulatta 99.9 1046
XP_001168194.1 PREDICTED: atrial natriuretic peptide receptor 2 isoform 2 P. troglodytes 99.9 1046
NP_776149.1 Npr2 gene product M. musculus 99.1 1046
NP_001084176.1 natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) X. laevis 84.7 1019
NP_001038402.1 atrial natriuretic peptide receptor 1 precursor D. rerio 73.3 1017
NP_650505.2 CG31183 D. melanogaster 65.1 682
NP_491380.1 Protein GCY-28, isoform b C. elegans 64.5 498
XP_001697314.1 guanylate cyclase C. reinhardtii 51.9 188
Other hits (2 of 38) [Show all]SpeciesId(%)Len(aa)
XP_001504537.1 PREDICTED: atrial natriuretic peptide receptor 2 E. caballus 99.3 1046
NP_446290.1 Npr2 gene product R. norvegicus 99.2 1046

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; eye; ovary; prostate; thyroid; uterus; adipose tissue; skin; ear; testis; mammary gland; liver; kidney; intestine; adrenal gland; larynx; heart; connective tissue; pancreas; umbilical cord; bone; lung; pituitary gland; uncharacterized tissue; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9p21-p12
UniSTS entry: Npr2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (3)

NM_003995.3 Homo sapiens natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) (NPR2), mRNA PA
BC023017.1 Homo sapiens natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B), mRNA (cDNA clone IMAGE:4939622), partial cds PA
L13436.1 Homo sapiens guanylate cyclase mRNA, complete mature peptide P

EST sequences (10 of 134) [Show all sequences]

AA994689.1 Clone IMAGE:1632011 mammary gland 3' read PA
R19620.1 Clone IMAGE:34645 brain 5' read
AI051689.1 Clone IMAGE:1673788 mixed 3' read
AI090222.1 Clone IMAGE:1697078 uterus 3' read P
AI199042.1 Clone IMAGE:1859506 brain 3' read
AI274470.1 Clone IMAGE:1986056 uterus 3' read
AI288159.1 Clone IMAGE:1986989 uterus 3' read
AI433910.1 Clone IMAGE:2130789 kidney 3' read P
R51752.1 Clone IMAGE:38928 brain 5' read P
R51753.1 Clone IMAGE:38928 brain 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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