> C-src tyrosine kinase (CSK)
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UGID:140148     UniGene Hs.77793     Homo sapiens (human)   CSK Order cDNA clone, Links
C-src tyrosine kinase (CSK)

Human protein-coding gene CSK. Represented by 499 ESTs from 206 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 140148 - Hs.77793]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_031809.2 tyrosine-protein kinase CSK M. musculus 100.0 449
XP_001101430.1 PREDICTED: tyrosine-protein kinase CSK-like isoform 1 M. mulatta 100.0 449
XP_003901257.1 PREDICTED: tyrosine-protein kinase CSK isoform 1 P. anubis 100.0 449
XP_001138334.3 PREDICTED: tyrosine-protein kinase CSK isoform 4 P. troglodytes 100.0 449
NP_001120662.1 CSK gene product H. sapiens 100.0 449
NP_001177102.1 c-src tyrosine kinase S. scrofa 99.8 449
XP_004017899.1 PREDICTED: tyrosine-protein kinase CSK O. aries 99.8 444
XP_544774.3 PREDICTED: tyrosine-protein kinase CSK isoform 4 C. lupus familiaris 99.7 370
NP_001025210.1 Csk gene product R. norvegicus 99.6 449
NP_001068865.1 CSK gene product B. taurus 99.6 449
NP_001071067.1 csk gene product D. rerio 90.9 449
NP_001079062.1 c-src tyrosine kinase X. laevis 88.4 449
NP_731607.1 C-terminal Src kinase, isoform I D. melanogaster 66.2 394
NP_001021778.1 Protein CSK-1 C. elegans 57.1 478
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_001492434.2 PREDICTED: tyrosine-protein kinase CSK E. caballus 99.5 370
XP_001365590.1 PREDICTED: tyrosine-protein kinase CSK M. domestica 98.2 449

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: blood; uncharacterized tissue; skin; brain; lung; testis; intestine; spleen; lymph node; pancreas; liver; larynx; mixed; tonsil; salivary gland; prostate; embryonic tissue; vascular; eye; lymph; mammary gland; thymus; placenta; uterus; cervix; stomach; ovary; connective tissue; thyroid; heart; bladder; trachea; kidney; bone; bone marrow; mouth; ascites; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q24.1
UniSTS entry: Chr 15 RH69961
UniSTS entry: Chr 15 MARC_5011-5012:996690037:1
UniSTS entry: Chr 15 PMC193924P3
UniSTS entry: Chr 15 CSK_3956
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

AK127672.1 Homo sapiens cDNA FLJ45770 fis, clone NETRP2002197, highly similar to Tyrosine-protein kinase CSK (EC 2.7.10.2) P
NM_004383.2 Homo sapiens c-src tyrosine kinase (CSK), transcript variant 1, mRNA PA
CR541960.1 Homo sapiens full open reading frame cDNA clone RZPDo834E0634D for gene CSK, c-src tyrosine kinase; complete cds, without stopcodon P
AK223626.1 Homo sapiens mRNA for c-src tyrosine kinase variant, clone: FCC134G03 P
AY007162.1 Homo sapiens clone CDABP0138 mRNA sequence PA
BC106073.1 Homo sapiens c-src tyrosine kinase, mRNA (cDNA clone MGC:117393 IMAGE:6526810), complete cds PA
BC104847.1 Homo sapiens c-src tyrosine kinase, mRNA (cDNA clone MGC:132507 IMAGE:8143850), complete cds P
BC104875.1 Homo sapiens c-src tyrosine kinase, mRNA (cDNA clone MGC:132535 IMAGE:8143878), complete cds P
AK290531.1 Homo sapiens cDNA FLJ78579 complete cds, highly similar to Homo sapiens c-src tyrosine kinase (CSK), mRNA P
AK310136.1 Homo sapiens cDNA, FLJ17178
AK312669.1 Homo sapiens cDNA, FLJ93062, Homo sapiens c-src tyrosine kinase (CSK), mRNA P
AK309344.1 Homo sapiens cDNA, FLJ99385 P
NM_001127190.1 Homo sapiens c-src tyrosine kinase (CSK), transcript variant 2, mRNA PA
X59932.1 Human mRNA for C-SRC-kinase PA
X60114.1 H.sapiens cyl mRNA for cytoplasmic tryrosine kinase P
AK298245.1 Homo sapiens cDNA FLJ51496 complete cds, highly similar to Tyrosine-protein kinase CSK (EC 2.7.10.2) P
AK297694.1 Homo sapiens cDNA FLJ55227 complete cds, highly similar to Tyrosine-protein kinase CSK (EC 2.7.10.2) P
AB451420.1 Homo sapiens CSK mRNA for c-src tyrosine kinase, partial cds, clone: FLJ08127AAAF P
AB451288.1 Homo sapiens CSK mRNA for c-src tyrosine kinase, complete cds, clone: FLJ08127AAAN P

EST sequences (10 of 499) [Show all sequences]

AA961901.1 Clone IMAGE:1598731 uncharacterized tissue 3' read
AA983394.1 Clone IMAGE:1598769 uncharacterized tissue 3' read A
AI025473.1 Clone IMAGE:1642347 testis 3' read A
T27116.1 Clone LLAB298B03 brain 5' read
T06085.1 Clone HFBDO23 brain P
AI139938.1 Clone IMAGE:1691897 heart 3' read A
BX111061.1 Clone IMAGp998E03400_;_IMAGE:206186 mixed
AI167415.1 Clone IMAGE:1661636 mixed 3' read
AI191891.1 Clone IMAGE:1734184 testis 3' read
AI252336.1 Clone IMAGE:1982790 ovary 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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