> Ubiquitin specific peptidase 4 (proto-oncogene) (USP4)
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UGID:140105     UniGene Hs.77500     Homo sapiens (human)   USP4 Order cDNA clone, Links
Ubiquitin specific peptidase 4 (proto-oncogene) (USP4)

Human protein-coding gene USP4. Represented by 468 ESTs from 219 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 140105 - Hs.77500]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003354.2 USP4 gene product H. sapiens 100.0 962
XP_001163445.1 PREDICTED: ubiquitin carboxyl-terminal hydrolase 4 isoform 8 P. troglodytes 100.0 961
NP_035808.2 Usp4 gene product M. musculus 95.7 961
XP_002662556.2 PREDICTED: ubiquitin carboxyl-terminal hydrolase 4 isoform 1 D. rerio 81.5 1008
NP_001082452.1 ubiquitin specific peptidase 4 (proto-oncogene) X. laevis 81.0 949
NP_174562.2 ubiquitin carboxyl-terminal hydrolase 4/11/15 A. thaliana 60.2 583
XP_001702430.1 predicted protein C. reinhardtii 59.6 346
NP_501035.1 Protein H34C03.2 C. elegans 58.1 258
NP_649153.1 CG8334, isoform A D. melanogaster 53.5 299
XP_956165.2 hypothetical protein NCU00480 N. crassa 53.1 877
NP_012338.1 Ubp12p S. cerevisiae 52.0 766
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
XP_003894489.1 PREDICTED: ubiquitin carboxyl-terminal hydrolase 4 P. anubis 99.1 920
XP_002802844.1 PREDICTED: ubiquitin carboxyl-terminal hydrolase 4-like M. mulatta 98.9 934

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; intestine; uncharacterized tissue; mixed; uterus; placenta; liver; ovary; kidney; connective tissue; adrenal gland; thyroid; eye; skin; lung; mammary gland; ear; pharynx; embryonic tissue; pancreas; lymph node; heart; muscle; prostate; vascular; adipose tissue; mouth; blood; bone marrow; thymus; spleen; stomach; trachea; ascites; nerve; lymph; salivary gland; cervix; bone; larynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3p21.3
UniSTS entry: Chr 3 STS-U20657 [Map Viewer]
UniSTS entry: Chr 3 SHGC-31529 [Map Viewer]
UniSTS entry: Chr 3 RH41918
UniSTS entry: Chr 3 RH45172
UniSTS entry: Chr 3 RH18550 [Map Viewer]
UniSTS entry: Chr 3 WI-14204 [Map Viewer]
UniSTS entry: Chr 3 USP4_8707
UniSTS entry: Chr 1 L17791
UniSTS entry: Chr 1 D8S2279
UniSTS entry: Chr 15 Rnu2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

NM_003363.3 Homo sapiens ubiquitin specific peptidase 4 (proto-oncogene) (USP4), transcript variant 1, mRNA P
NM_199443.2 Homo sapiens ubiquitin specific peptidase 4 (proto-oncogene) (USP4), transcript variant 2, mRNA P
BC068017.1 Homo sapiens ubiquitin specific peptidase 4 (proto-oncogene), mRNA (cDNA clone IMAGE:5215992), with apparent retained intron PA
AK223292.1 Homo sapiens mRNA for ubiquitin specific protease, proto-oncogene isoform a variant, clone: SYN05029 PA
AK222725.1 Homo sapiens mRNA for ubiquitin specific protease, proto-oncogene isoform b variant, clone: COL07356 PA
BC125131.1 Homo sapiens ubiquitin specific peptidase 4 (proto-oncogene), mRNA (cDNA clone MGC:149849 IMAGE:40119091), complete cds P
BC125130.1 Homo sapiens ubiquitin specific peptidase 4 (proto-oncogene), mRNA (cDNA clone MGC:149848 IMAGE:40119090), complete cds P
U20657.1 Human ubiquitin protease (Unph) proto-oncogene mRNA, complete cds P
BC110070.1 Homo sapiens cDNA clone IMAGE:40014994 P
AK291795.1 Homo sapiens cDNA FLJ78681 complete cds, highly similar to Homo sapiens ubiquitin specific peptidase 4 (proto-oncogene) (USP4), transcript variant 1, mRNA P
NM_001251877.1 Homo sapiens ubiquitin specific peptidase 4 (proto-oncogene) (USP4), transcript variant 3, mRNA PA
AF017305.1 Homo sapiens deubiquitinating enzyme UnpEL (UNP) mRNA, complete cds P
AF017306.1 Homo sapiens deubiquitinating enzyme UnpES (UNP) mRNA, complete cds P

EST sequences (10 of 468) [Show all sequences]

AA994871.1 Clone IMAGE:1625511 mixed 3' read
AI000913.1 Clone IMAGE:1610368 mammary gland 3' read
AI015636.1 Clone IMAGE:1638789 testis 3' read P
AA927700.1 Clone IMAGE:1552719 uncharacterized tissue 3' read P
AI097283.1 Clone IMAGE:1707205 heart 3' read
AI123184.1 Clone IMAGE:1693673 heart 3' read
AI129625.1 Clone IMAGE:1712908 uterus 3' read P
AI139057.1 Clone IMAGE:1710389 uterus 3' read P
AI139616.1 Clone IMAGE:1735713 testis 3' read P
AI146684.1 Clone IMAGE:1697933 uterus 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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