Aldehyde dehydrogenase 4 family, member A1 (ALDH4A1)

NCBI

UniGene
Homepage
FAQs
Query Tips
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
dbEST
Trace Archive

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs

UGID:140098 UniGene Hs.77448 Homo sapiens (human) ALDH4A1

Order cDNA clone, Links

Aldehyde dehydrogenase 4 family, member A1 (ALDH4A1)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_003739.2	aldehyde dehydrogenase 4A1 isoform a precursor	H. sapiens	100.0	562
NP_780647.3	aldehyde dehydrogenase 4A1 precursor	M. musculus	94.5	561
NP_001090548.1	aldehyde dehydrogenase 4A1	X. laevis	83.8	553
NP_957452.1	aldehyde dehydrogenase 4A1 precursor	D. rerio	82.0	554
NP_730695.1	CG7145, isoform A	D. melanogaster	68.2	532
NP_493946.1	ALdehyde deHydrogenase family member (alh-6)	C. elegans	63.5	558
XP_330512.1	hypothetical protein	N. crassa	53.9	558
NP_011902.1	Delta-1-pyrroline-5-carboxylate dehydrogenase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; deficiency of the human homolog causes HPII, an autosomal recessive inborn error of metabolism; Put2p	S. cerevisiae	50.2	570

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; kidney; placenta; liver; thymus; mixed; prostate; uncharacterized tissue; mouth; testis; skin; adrenal gland; connective tissue; eye; embryonic tissue; esophagus; lung; spleen; blood; heart; uterus; mammary gland; intestine; umbilical cord; trachea; cervix; muscle; larynx; bladder; ascites; stomach; ovary; nerve; bone; vascular; thyroid; bone marrow

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	1
Map position:	1p36
UniSTS entry:	Chr 1	SHGC-74312
UniSTS entry:	Chr 1	RH80741

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

NM_003748.3	Homo sapiens aldehyde dehydrogenase 4 family, member A1 (ALDH4A1), nuclear gene encoding mitochondrial protein, transcript variant P5CDhL, mRNA	PA
AK222486.1	Homo sapiens mRNA for aldehyde dehydrogenase 4A1 precursor variant, clone: adKA03036	P
BC007581.1	Homo sapiens aldehyde dehydrogenase 4 family, member A1, mRNA (cDNA clone MGC:15564 IMAGE:3139944), complete cds	PA
U24266.1	Human pyrroline-5-carboxylate dehydrogenase (P5CDh) mRNA, long form, complete cds	P
U24267.1	Human pyrroline-5-carboxylate dehydrogenase (P5CDh) mRNA, short form, complete cds	P
AK289972.1	Homo sapiens cDNA FLJ75077 complete cds, highly similar to Homo sapiens aldehyde dehydrogenase 4 family, member A1, transcript variant P5CDhL, mRNA	PA
AK294552.1	Homo sapiens cDNA FLJ54479 complete cds, highly similar to Delta-1-pyrroline-5-carboxylatedehydrogenase, mitochondrial precursor (EC 1.5.1.12)	P
NM_001161504.1	Homo sapiens aldehyde dehydrogenase 4 family, member A1 (ALDH4A1), transcript variant 3, mRNA	PA
BC023600.2	Homo sapiens aldehyde dehydrogenase 4 family, member A1, mRNA (cDNA clone MGC:23086 IMAGE:4548787), complete cds	PA
NM_170726.2	Homo sapiens aldehyde dehydrogenase 4 family, member A1 (ALDH4A1), nuclear gene encoding mitochondrial protein, transcript variant P5CDhS, mRNA	PA

EST sequences (10 of 694) [Show all sequences]

AA971729.1	Clone IMAGE:1584608	lung	3' read	A
R20304.1	Clone IMAGE:32923	brain	5' read
AI080210.1	Clone IMAGE:1677370	mixed	3' read	A
AI090813.1	Clone IMAGE:1692227	heart	3' read	A
AI142342.1	Clone IMAGE:1839890	testis	5' read
AI144444.1	Clone IMAGE:1708877	heart	3' read	A
AI147334.1	Clone IMAGE:1839890	testis	3' read	A
AI147495.1	Clone IMAGE:1693991	heart	3' read	A
BX098144.1	Clone IMAGp998B20113_;_IMAGE:121267	mixed
AI268982.1	Clone IMAGE:1864555	kidney	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria