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UGID:139990     UniGene Hs.76392     Homo sapiens (human)   ALDH1A1
Aldehyde dehydrogenase 1 family, member A1 (ALDH1A1)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_001142597.1 PREDICTED: aldehyde dehydrogenase 1A1 isoform 2 P. troglodytes 100.0 500
NP_000680.2 aldehyde dehydrogenase 1A1 H. sapiens 100.0 500
XP_001097512.1 PREDICTED: aldehyde dehydrogenase 1A1 isoform 5 M. mulatta 99.8 500
NP_038495.2 aldehyde dehydrogenase 1A1 M. musculus 92.8 500
NP_001081240.1 aldehyde dehydrogenase class 1 X. laevis 85.3 501
NP_571925.1 aldehyde dehydrogenase 1A2 D. rerio 81.9 514
NP_498081.2 ALdehyde deHydrogenase family member (alh-1) C. elegans 73.5 508
NP_609285.1 aldehyde dehydrogenase D. melanogaster 70.8 510
NP_190383.1 ALDH2B4 (ALDEHYDE DEHYDROGENASE 2B4); 3-chloroallyl aldehyde dehydrogenase/ ATP binding / aldehyde dehydrogenase (NAD) A. thaliana 65.3 507
XP_001690955.1 aldehyde dehydrogenase C. reinhardtii 63.8 518
XP_322673.1 hypothetical protein N. crassa 63.8 493
NP_013893.1 Cytoplasmic aldehyde dehydrogenase, involved in ethanol oxidation and beta-alanine biosynthesis; uses NAD+ as the preferred coenzyme; expression is stress induced and glucose repressed; very similar to Ald3p; Ald2p S. cerevisiae 58.1 505

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; liver; intestine; testis; uterus; lung; kidney; trachea; stomach; adrenal gland; connective tissue; eye; spleen; mixed; skin; pancreas; mouth; vascular; prostate; uncharacterized tissue; placenta; bladder; pharynx; ear; heart; thymus; blood; ovary; salivary gland; mammary gland; bone marrow; muscle; pituitary gland; bone; thyroid; larynx; ascites; cervix; adipose tissue; ganglia; embryonic tissue; esophagus; nerve; umbilical cord; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9q21.13
UniSTS entry: Chr 9 HUM00D1B06
UniSTS entry: Chr 9 RH12740
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BT006921.1 Homo sapiens aldehyde dehydrogenase 1 family, member A1 mRNA, complete cds P
NM_000689.3 Homo sapiens aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), mRNA PA
K03000.1 Human aldehyde dehydrogenase 1 mRNA P
AY390731.1 Homo sapiens aldehyde dehydrogenase 1 A1 mRNA, complete cds P
AK000118.1 Homo sapiens cDNA FLJ20111 fis, clone COL05226, highly similar to K03000 Human aldehyde dehydrogenase 1 mRNA PA
CR601139.1 full-length cDNA clone CS0DI021YH08 of Placenta Cot 25-normalized of Homo sapiens (human) P
AB209821.1 Homo sapiens mRNA for aldehyde dehydrogenase 1A1 variant protein P
AK026641.1 Homo sapiens cDNA: FLJ22988 fis, clone KAT11812 PA
BC001505.2 Homo sapiens aldehyde dehydrogenase 1 family, member A1, mRNA (cDNA clone MGC:2318 IMAGE:2988388), complete cds PA
AK293176.1 Homo sapiens cDNA FLJ51786 complete cds, highly similar to Retinal dehydrogenase 1 (EC 1.2.1.36) P
AK302168.1 Homo sapiens cDNA FLJ50286 complete cds, highly similar to Retinal dehydrogenase 1 (EC 1.2.1.36) P
M26761.1 Human aldehyde dehydrogenase I (ALDH-1) mRNA, 3' end P
AF003341.1 Homo sapiens aldehyde dehydrogenase 1 (ALDH1) mRNA, complete cds P

EST sequences (10 of 2767) [Show all sequences]

AA954716.1 Clone IMAGE:1572866 kidney 3' read A
AA903116.1 Clone IMAGE:1517567 uncharacterized tissue 3' read A
AI000394.1 Clone IMAGE:1614084 uncharacterized tissue 3' read A
R17640.1 Clone IMAGE:32255 brain 5' read P
AI017754.1 Clone IMAGE:1638994 testis 3' read A
AI022879.1 Clone IMAGE:1650647 parathyroid 3' read A
AI040307.1 Clone IMAGE:1665319 skin 3' read
AI041783.1 Clone IMAGE:1665393 skin 3' read
AI050734.1 Clone IMAGE:1663957 skin 3' read P
AI074764.1 Clone IMAGE:1666904 skin 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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