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UGID:139929     UniGene Hs.75862     Homo sapiens (human)   SMAD4 Order cDNA clone, Links
SMAD family member 4 (SMAD4)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_001096439.1 PREDICTED: mothers against decapentaplegic homolog 4 isoform 2 M. mulatta 100.0 551
XP_523926.2 PREDICTED: mothers against decapentaplegic homolog 4 isoform 7 P. troglodytes 100.0 551
NP_005350.1 mothers against decapentaplegic homolog 4 H. sapiens 100.0 551
NP_062148.1 SMAD family member 4 R. norvegicus 99.8 551
XP_849370.1 PREDICTED: similar to Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Smad4) isoform 2 C. lupus familiaris 99.8 551
XP_001499937.1 PREDICTED: similar to smad4 E. caballus 99.8 551
NP_999237.1 mothers against decapentaplegic homolog 4 S. scrofa 99.8 551
NP_001069677.1 mothers against decapentaplegic homolog 4 B. taurus 99.6 552
XP_001479733.1 PREDICTED: similar to MAD homolog 4 (Drosophila) isoform 1 M. musculus 99.6 550
NP_001090536.1 XSmad4a protein X. laevis 98.2 548
XP_001923003.1 PREDICTED: Smad4 D. rerio 97.4 546
NP_733438.1 medea, isoform B D. melanogaster 82.2 660
NP_001040865.1 SMAll family member (sma-4) C. elegans 45.0 180

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; embryonic tissue; mixed; testis; kidney; connective tissue; trachea; prostate; lung; muscle; parathyroid; pancreas; placenta; ear; uterus; liver; pharynx; mammary gland; uncharacterized tissue; mouth; skin; spleen; intestine; pituitary gland; salivary gland; bladder; vascular; thymus; thyroid; ovary; eye; lymph node; blood; stomach; heart; bone marrow; cervix; spinal cord; tonsil; lymph; bone; ascites; nerve; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 18
Map position: 18q21.1
UniSTS entry: Chr 18 D18S903E
UniSTS entry: Chr 18 (n/a)
UniSTS entry: Chr 18 PMC86557P1
UniSTS entry: Chr 18 RH75869
UniSTS entry: Chr 18 (n/a)
UniSTS entry: Chr 18 D18S1110
UniSTS entry: Chr 18 RH66749
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

BX647129.1 Homo sapiens mRNA; cDNA DKFZp686A13166 (from clone DKFZp686A13166) PA
NM_005359.5 Homo sapiens SMAD family member 4 (SMAD4), mRNA PA
U44378.1 Human homozygous deletion target in pancreatic carcinoma (DPC4) mRNA, complete cds P
BC002379.2 Homo sapiens SMAD family member 4, mRNA (cDNA clone MGC:8602 IMAGE:2961238), complete cds PA
AK290770.1 Homo sapiens cDNA FLJ76143 complete cds, highly similar to Homo sapiens SMAD, mothers against DPP homolog 4 (SMAD4), mRNA PA
AL832789.1 Homo sapiens mRNA; cDNA DKFZp667E0923 (from clone DKFZp667E0923) PA
AK303027.1 Homo sapiens cDNA FLJ59261 complete cds, highly similar to Mothers against decapentaplegic homolog 4 (SMAD4) P

EST sequences (10 of 464) [Show all sequences]

AA954421.1 Clone IMAGE:1563449 mixed 3' read P
AA972906.1 Clone IMAGE:1578941 mixed 3' read A
AI016049.1 Clone IMAGE:1636198 kidney 3' read A
AA909479.1 Clone IMAGE:1523604 mixed 3' read A
AI079973.1 Clone IMAGE:1678396 mixed 3' read
R21589.1 Clone IMAGE:31399 brain 5' read
AI123254.1 Clone IMAGE:1689946 mixed 3' read
CB051706.1 Clone IMAGE:3289819 uncharacterized tissue 5' read
BX096310.1 Clone IMAGp998L23728_;_IMAGE:321958 parathyroid
BX111778.1 Clone IMAGp998F13667_;_IMAGE:298380 lung


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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