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Myosin, light chain 2, regulatory, cardiac, slow (MYL2)
Human protein-coding gene MYL2. Represented by 670 ESTs from 57 cDNA libraries. Corresponds to reference sequence NM_000432.3. [UniGene 139847 - Hs.75535]
SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
| Best Hits and Hits from model organisms | Species | Id(%) | Len(aa) |
|
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MYL2 gene product |
H. sapiens |
100.0 |
165 |
|
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Myl2 gene product |
M. musculus |
98.2 |
165 |
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PREDICTED: myosin regulatory light chain 2, ventricular/cardiac muscle isoform-like, partial |
D. rerio |
92.4 |
170 |
|
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myosin, light chain 2, regulatory, cardiac, slow |
X. laevis |
92.2 |
166 |
|
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Protein MLC-4 |
C. elegans |
59.6 |
171 |
|
|
spaghetti squash |
D. melanogaster |
59.1 |
163 |
| Other hits (2 of 39) [Show all] | Species | Id(%) | Len(aa) |
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PREDICTED: Myosin regulatory light chain 2, ventricular/cardiac muscle isoform-like |
O. cuniculus |
99.4 |
165 |
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PREDICTED: myosin regulatory light chain 2, ventricular/cardiac muscle isoform |
M. mulatta |
98.8 |
165 |
GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
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EST Profile: | Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this] |
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GEO Profiles: |
Experimental gene expression data (Gene Expression Omnibus). |
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cDNA Sources: |
heart; muscle; liver; larynx; prostate; epididymis; lung; mixed; mouth; pancreas; eye; nerve; testis; bone; peritoneum; embryonic tissue; uncharacterized tissue; vascular; lymph node; mammary gland; ovary; kidney |
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.
mRNA sequences (14)
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X57542.1 |
H.sapiens ventricular myosin light chain 2 mRNA |
P |
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BX538165.1 |
Homo sapiens mRNA; cDNA DKFZp779C0562 (from clone DKFZp779C0562) |
A |
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NM_000432.3 |
Homo sapiens myosin, light chain 2, regulatory, cardiac, slow (MYL2), mRNA |
PA |
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CR456962.1 |
Homo sapiens full open reading frame cDNA clone RZPDo834B025D for gene MYL2, myosin, light polypeptide 2, regulatory, cardiac, slow; complete cds, incl. stopcodon |
P |
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CR541957.1 |
Homo sapiens full open reading frame cDNA clone RZPDo834H0434D for gene MYL2, myosin, light polypeptide 2, regulatory, cardiac, slow; complete cds, without stopcodon |
P |
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M22815.1 |
Human (clone PWHCLC2-8) cardiac myosin light chain 2 mRNA, complete cds |
P |
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BC015821.1 |
Homo sapiens myosin, light chain 2, regulatory, cardiac, slow, mRNA (cDNA clone MGC:13576 IMAGE:4245364), complete cds |
PA |
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AK312013.1 |
Homo sapiens cDNA, FLJ92288, highly similar to Homo sapiens myosin, light polypeptide 2, regulatory, cardiac, slow (MYL2), mRNA |
P |
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BC031006.1 |
Homo sapiens myosin, light chain 2, regulatory, cardiac, slow, mRNA (cDNA clone MGC:32746 IMAGE:4292208), complete cds |
PA |
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BC031008.1 |
Homo sapiens myosin, light chain 2, regulatory, cardiac, slow, mRNA (cDNA clone MGC:32751 IMAGE:4297454), complete cds |
PA |
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X14332.1 |
Human mRNA for ventricular myosin light chain 2 |
P |
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X66141.1 |
H.sapiens mRNA for cardiac ventricular myosin light chain-2 |
PA |
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S69022.1 |
Homo sapiens myosin light chain-2 mRNA, complete cds |
P |
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AF020768.1 |
Homo sapiens cardiac ventricular myosin light chain 2 mRNA, complete cds |
P |
EST sequences (10 of 670) [Show all sequences]
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AI052734.1 |
Clone IMAGE:1676541 |
embryonic tissue |
3' read |
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AI092678.1 |
Clone IMAGE:1693069 |
heart |
3' read |
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AI126938.1 |
Clone IMAGE:1707914 |
heart |
3' read |
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CB049406.1 |
Clone IMAGE:3271431 |
prostate |
5' read |
P |
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CB049405.1 |
Clone IMAGE:3271431 |
prostate |
3' read |
PA |
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AI160422.1 |
Clone IMAGE:1709022 |
heart |
3' read |
PA |
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BX090583.1 |
Clone IMAGp998L04671_;_IMAGE:300051 |
lung |
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P |
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AI186180.1 |
Clone IMAGE:1742035 |
lung |
3' read |
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AI190480.1 |
Clone IMAGE:1731760 |
heart |
3' read |
PA |
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AI198711.1 |
Clone IMAGE:1756108 |
lung |
3' read |
A |
Key to Symbols
P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria
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