> Purine nucleoside phosphorylase (PNP)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:139842     UniGene Hs.75514     Homo sapiens (human)   PNP Order cDNA clone, Links
Purine nucleoside phosphorylase (PNP)

Human protein-coding gene PNP. Represented by 713 ESTs from 283 cDNA libraries. Corresponds to reference sequence NM_000270.3. [UniGene 139842 - Hs.75514]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001140576.1 PREDICTED: purine nucleoside phosphorylase isoform 2 P. troglodytes 100.0 288
NP_000261.2 PNP gene product H. sapiens 100.0 288
NP_038660.1 Pnp gene product M. musculus 88.6 288
NP_991218.2 pnp6 gene product D. rerio 72.3 278
NP_001079809.1 purine nucleoside phosphorylase X. laevis 72.1 246
NP_728752.1 CG16758, isoform D D. melanogaster 58.7 315
NP_013310.1 purine-nucleoside phosphorylase S. cerevisiae 56.5 282
NP_499900.1 Protein K02D7.1 C. elegans 50.8 259
Other hits (2 of 42) [Show all]SpeciesId(%)Len(aa)
XP_001092508.1 PREDICTED: purine nucleoside phosphorylase isoform 1 M. mulatta 97.2 288
XP_003901540.1 PREDICTED: purine nucleoside phosphorylase P. anubis 96.9 288

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mixed; placenta; uncharacterized tissue; brain; ascites; blood; intestine; lung; liver; salivary gland; skin; thyroid; kidney; connective tissue; uterus; embryonic tissue; eye; larynx; mouth; mammary gland; trachea; bone marrow; heart; pharynx; prostate; adipose tissue; lymph; pancreas; stomach; ovary; thymus; vascular; lymph node; umbilical cord; parathyroid; cervix; testis; spleen; bone; adrenal gland; ganglia; peritoneum; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 14
Map position: 14q13.1
UniSTS entry: Chr 14 NP
UniSTS entry: Chr 14 RH18070
UniSTS entry: Chr 14 RH78901 [Map Viewer]
UniSTS entry: Chr 14 SHGC-31518 [Map Viewer]
UniSTS entry: Chr 14 GDB:181553
UniSTS entry: Chr 14 humpnu2
UniSTS entry: Chr 14 SHGC-78026
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AK126154.1 Homo sapiens cDNA FLJ44166 fis, clone THYMU2033583, highly similar to Purine nucleoside phosphorylase (EC 2.4.2.1) P
NM_000270.3 Homo sapiens purine nucleoside phosphorylase (PNP), mRNA PA
CR407607.1 Homo sapiens full open reading frame cDNA clone RZPDo834A062D for gene NP, nucleoside phosphorylase complete cds, without stopcodon P
BC104207.1 Homo sapiens nucleoside phosphorylase, mRNA (cDNA clone MGC:125916 IMAGE:40031417), complete cds P
BC104206.1 Homo sapiens nucleoside phosphorylase, mRNA (cDNA clone MGC:125915 IMAGE:40031416), complete cds P
BC106074.1 Homo sapiens nucleoside phosphorylase, mRNA (cDNA clone MGC:117396 IMAGE:3859664), complete cds PA
AK313490.1 Homo sapiens cDNA, FLJ94043, Homo sapiens nucleoside phosphorylase (NP), mRNA P
AK307364.1 Homo sapiens cDNA, FLJ97312
AK307340.1 Homo sapiens cDNA, FLJ97288 P
AK098544.1 Homo sapiens cDNA FLJ25678 fis, clone TST04067, highly similar to PURINE NUCLEOSIDE PHOSPHORYLASE (EC 2.4.2.1) P
X00737.1 Human mRNA for purine nucleoside phosphorylase (PNP; EC 2.4.2.1) P

EST sequences (10 of 713) [Show all sequences]

AA954388.1 Clone IMAGE:1564898 mixed 3' read
AA970746.1 Clone IMAGE:1573123 kidney 3' read
AA972548.1 Clone IMAGE:1582957 mixed 3' read
AA975804.1 Clone IMAGE:1589518 kidney 3' read A
AI000814.1 Clone IMAGE:1637733 mammary gland 3' read
AI024906.1 Clone IMAGE:1631437 mammary gland 3' read P
AI077604.1 Clone IMAGE:1666958 skin 3' read
AI096488.1 Clone IMAGE:1685675 brain 3' read A
R22404.1 Clone IMAGE:130540 placenta 3' read A
R22453.1 Clone IMAGE:130540 placenta 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help