> Amyloid beta (A4) precursor-like protein 1 (APLP1)
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UGID:139684     UniGene Hs.74565     Homo sapiens (human)   APLP1 Order cDNA clone, Links
Amyloid beta (A4) precursor-like protein 1 (APLP1)

Human protein-coding gene APLP1. Represented by 960 ESTs from 143 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 139684 - Hs.74565]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001019978.1 APLP1 gene product H. sapiens 100.0 650
XP_003316371.1 PREDICTED: amyloid beta (A4) precursor-like protein 1 isoform 1 P. troglodytes 99.8 649
NP_031493.2 Aplp1 gene product M. musculus 95.1 653
XP_001342921.4 PREDICTED: amyloid beta A4 protein D. rerio 60.6 720
NP_001089419.1 amyloid beta (A4) precursor-like protein 1 precursor X. laevis 60.2 625
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
XP_003915417.1 PREDICTED: amyloid-like protein 1 isoform 1 P. anubis 98.8 652
XP_001099423.1 PREDICTED: amyloid beta (A4) precursor-like protein 1 isoform 1 M. mulatta 98.6 652

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; pancreas; eye; kidney; uncharacterized tissue; testis; cervix; lung; uterus; pituitary gland; mixed; liver; thyroid; nerve; ovary; embryonic tissue; stomach; intestine; bone; prostate; blood; skin; connective tissue; placenta; ganglia; muscle
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19q13.1
UniSTS entry: Chr 19 SHGC-4198
UniSTS entry: Chr 19 HSC0VF102 [Map Viewer]
UniSTS entry: Chr 19 RH66352
UniSTS entry: Chr 19 D19S237E
UniSTS entry: Chr 19 D19S237E
UniSTS entry: Chr 19 SHGC-30131 [Map Viewer]
UniSTS entry: Chr 19 D1S357E
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

NM_005166.3 Homo sapiens amyloid beta (A4) precursor-like protein 1 (APLP1), transcript variant 2, mRNA P
NM_001024807.1 Homo sapiens amyloid beta (A4) precursor-like protein 1 (APLP1), transcript variant 1, mRNA P
U48437.1 Homo sapiens amyloid precursor-like protein 1 (APLP1) mRNA, complete cds PA
EF036503.1 Homo sapiens amyloid precursor-like protein 1 isoform 1 precursor, mRNA, partial cds P
BC012889.1 Homo sapiens amyloid beta (A4) precursor-like protein 1, mRNA (cDNA clone MGC:9166 IMAGE:3865417), complete cds PA
AK312292.1 Homo sapiens cDNA, FLJ92596, highly similar to Homo sapiens amyloid beta (A4) precursor-like protein 1 (APLP1),mRNA P
AK092376.1 Homo sapiens cDNA FLJ35057 fis, clone OCBBF2018663, highly similar to AMYLOID-LIKE PROTEIN 1 PRECURSOR P
BC032983.1 Homo sapiens amyloid beta (A4) precursor-like protein 1, mRNA (cDNA clone IMAGE:4796713) P
BC013850.1 Homo sapiens amyloid beta (A4) precursor-like protein 1, mRNA (cDNA clone IMAGE:4180020) PA
AK297640.1 Homo sapiens cDNA FLJ56116 complete cds, highly similar to Amyloid-like protein 1 precursor (APLP)(APLP-1) [Contains: C30] P
AK297339.1 Homo sapiens cDNA FLJ56046 complete cds, highly similar to Amyloid-like protein 1 precursor (APLP)(APLP-1) [Contains: C30] P

EST sequences (10 of 960) [Show all sequences]

R14110.1 Clone IMAGE:27426 brain 5' read
AA984541.1 Clone IMAGE:1630197 brain 3' read P
AA984717.1 Clone IMAGE:1630359 brain 3' read P
AI066679.1 Clone IMAGE:1682305 skin 3' read A
AI126642.1 Clone IMAGE:1736080 testis 3' read A
BX115494.1 Clone IMAGp998A23172_;_IMAGE:40624 brain A
CB152094.1 Clone B1T694954-18-C10 brain 5' read P
CB152047.1 Clone B1T694954-17-F07 brain 5' read P
CB152903.1 Clone B1T694954-16-C04 brain 5' read P
CB153701.1 Clone B1T694954-26-G11 brain 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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