> Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide (YWHAQ)
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UGID:139667     UniGene Hs.74405     Homo sapiens (human)   YWHAQ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide (YWHAQ)

Human protein-coding gene YWHAQ. Represented by 1999 ESTs from 470 cDNA libraries. Corresponds to reference sequence NM_006826.2. [UniGene 139667 - Hs.74405]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_035869.1 14-3-3 protein theta M. musculus 100.0 244
NP_037185.1 Ywhaq gene product R. norvegicus 100.0 244
XP_003308926.1 PREDICTED: 14-3-3 protein theta isoform 1 P. troglodytes 100.0 244
NP_006817.1 YWHAQ gene product H. sapiens 100.0 244
XP_532871.1 PREDICTED: 14-3-3 protein theta isoform 1 C. lupus familiaris 100.0 244
XP_001503630.1 PREDICTED: 14-3-3 protein theta-like E. caballus 100.0 244
XP_003481338.1 PREDICTED: 14-3-3 protein theta isoform 1 S. scrofa 100.0 244
NP_001071595.1 YWHAQ gene product B. taurus 100.0 244
NP_001075637.1 YWHAQ gene product O. cuniculus 100.0 244
XP_002197936.1 PREDICTED: 14-3-3 protein theta T. guttata 99.6 244
NP_001006415.1 YWHAQ gene product G. gallus 99.6 244
XP_003204530.1 PREDICTED: 14-3-3 protein theta-like M. gallopavo 99.6 244
XP_001097635.1 PREDICTED: 14-3-3 protein theta isoform 1 M. mulatta 99.6 244
NP_958892.1 ywhaqb gene product D. rerio 86.9 244
NP_001080117.1 14-3-3 protein zeta a X. laevis 82.5 244
NP_476885.2 14-3-3zeta, isoform D D. melanogaster 82.2 246
NP_509939.1 Protein FTT-2, isoform a C. elegans 81.6 244
XP_964462.1 14-3-3 protein 7 N. crassa 72.1 247
XP_001702812.1 14-3-3 protein C. reinhardtii 71.3 254
NP_851274.1 14-3-3-like protein GF14 kappa A. thaliana 69.2 246
NP_011104.3 Bmh1p S. cerevisiae 68.8 266
Other hits (2 of 56) [Show all]SpeciesId(%)Len(aa)
XP_001381163.2 PREDICTED: 14-3-3 protein theta-like M. domestica 99.2 244
XP_004023741.1 PREDICTED: LOW QUALITY PROTEIN: 14-3-3 protein theta O. aries 99.2 241

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; embryonic tissue; pancreas; skin; uncharacterized tissue; uterus; placenta; blood; lung; eye; prostate; lymph node; intestine; mammary gland; mixed; connective tissue; kidney; liver; stomach; bone; ovary; thyroid; bone marrow; bladder; heart; muscle; vascular; cervix; adrenal gland; thymus; lymph; larynx; mouth; ear; ascites; salivary gland; nerve; ganglia; umbilical cord; parathyroid; pharynx; pituitary gland; esophagus; epididymis; pineal gland; tonsil; adipose tissue; trachea
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2p25.1
UniSTS entry: Chr 4 RH126547
UniSTS entry: Chr 10 D10S2166
UniSTS entry: Chr 10 D22S1126
UniSTS entry: Chr 10 RH70237
UniSTS entry: Chr 10 RH15607
UniSTS entry: Chr 2 YWHAQ_1656
UniSTS entry: Ywhaq
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AF070556.1 Homo sapiens clone 24409 14.3.3 protein mRNA, partial cds PA
BC050601.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide, mRNA (cDNA clone MGC:60050 IMAGE:6501365), complete cds PA
BC056867.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide, mRNA (cDNA clone MGC:64844 IMAGE:6164592), complete cds PA
NM_006826.2 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide (YWHAQ), mRNA P
BT020014.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide mRNA, complete cds P
BC093019.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide, mRNA (cDNA clone MGC:110899 IMAGE:30520472), complete cds PA
AK309462.1 Homo sapiens cDNA, FLJ99503 PA
X56468.1 Human mRNA for 14.3.3 protein, a protein kinase regulator P
AK297624.1 Homo sapiens cDNA FLJ52118 complete cds, highly similar to 14-3-3 protein theta P
AK302208.1 Homo sapiens cDNA FLJ51144 complete cds, highly similar to 14-3-3 protein theta P
X57347.1 H.sapiens mRNA for HS1 protein PA
AK316158.1 Homo sapiens cDNA, FLJ79057 complete cds, highly similar to 14-3-3 protein theta P

EST sequences (10 of 1999) [Show all sequences]

AA862500.1 Clone IMAGE:1456992 kidney 3' read
AA975963.1 Clone IMAGE:1568064 lung 3' read
AA988496.1 Clone IMAGE:1603025 lung 3' read A
R16291.1 Clone IMAGE:29982 brain 5' read
AA995369.1 Clone IMAGE:1601568 lung 3' read P
AA911251.1 Clone IMAGE:1521003 lung 3' read
AI003524.1 Clone IMAGE:1699132 kidney 3' read A
AI003161.1 Clone IMAGE:1700031 kidney 3' read A
AI015981.1 Clone IMAGE:1635584 kidney 3' read P
AA922814.1 Clone IMAGE:1551991 uncharacterized tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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