THAP domain containing, apoptosis associated protein 1 (THAP1)

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UGID:132126 UniGene Hs.7432 Homo sapiens (human) THAP1

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THAP domain containing, apoptosis associated protein 1 (THAP1)

Human protein-coding gene THAP1. Represented by 104 ESTs from 73 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 132126 - Hs.7432]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_528123.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: uncharacterized protein LOC472751	P. troglodytes	100.0	212
NP_060575.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	THAP1 gene product	H. sapiens	100.0	212
XP_001099355.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: THAP domain-containing protein 1	M. mulatta	100.0	211
XP_003902757.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: THAP domain-containing protein 1	P. anubis	100.0	211
NP_950243.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Thap1 gene product	M. musculus	96.2	209
NP_001088492.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	THAP domain-containing protein 1 A	X. laevis	78.3	212
Other hits (2 of 17) [Show all]		Species	Id(%)	Len(aa)
XP_003359917.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: THAP domain-containing protein 1-like	S. scrofa	99.1	212
XP_001915290.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: THAP domain-containing protein 1-like	E. caballus	99.0	190

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; uncharacterized tissue; mixed; kidney; stomach; muscle; vascular; lymph; mammary gland; thyroid; testis; eye; intestine; embryonic tissue; pharynx; placenta; heart; prostate; lung; salivary gland; bone; skin; lymph node; liver; blood; uterus; connective tissue

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	8
Map position:	8p11.21
UniSTS entry:	Chr 8	RH66246
UniSTS entry:	Chr 8	G19704
UniSTS entry:	Chr 8	RH10510
UniSTS entry:	Chr 8	THAP1_9880

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_199003.1	Homo sapiens THAP domain containing, apoptosis associated protein 1 (THAP1), transcript variant 2, mRNA	PA
AK001339.1	Homo sapiens cDNA FLJ10477 fis, clone NT2RP2000097	P
CR457256.1	Homo sapiens full open reading frame cDNA clone RZPDo834D119D for gene THAP1, THAP domain containing, apoptosis associated protein 1; complete cds, incl. stopcodon	P
NM_018105.2	Homo sapiens THAP domain containing, apoptosis associated protein 1 (THAP1), transcript variant 1, mRNA	PA
AK223231.1	Homo sapiens mRNA for THAP domain containing, apoptosis associated protein 1 isoform 1 variant, clone: STM02759	P
BC021721.2	Homo sapiens THAP domain containing, apoptosis associated protein 1, mRNA (cDNA clone MGC:33014 IMAGE:4795229), complete cds	PA
AL832077.1	Homo sapiens mRNA; cDNA DKFZp313G1223 (from clone DKFZp313G1223)	PA

EST sequences (10 of 104) [Show all sequences]

AI095609.1	Clone IMAGE:1697194	uterus	3' read	P
T06301.1	Clone HFBDR59	brain
AI392800.1	Clone IMAGE:2107842	uncharacterized tissue	3' read	A
AI475984.1	Clone IMAGE:2154922	intestine	3' read	A
AI497677.1	Clone IMAGE:2163209	brain	3' read	PA
R58374.1	Clone G3247	heart	5' read
AI763325.1	Clone IMAGE:2394127	intestine	3' read	A
AI887001.1	Clone IMAGE:2432648	brain	3' read	A
CB993371.1	Clone IMAGE:30339588	placenta	5' read	P
CB995843.1	Clone IMAGE:30335127	placenta	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria