> Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 (GNAI3)
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UGID:139588     UniGene Hs.73799     Homo sapiens (human)   GNAI3 Order cDNA clone, Links
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 (GNAI3)

Human protein-coding gene GNAI3. Represented by 1408 ESTs from 344 cDNA libraries. Corresponds to reference sequence NM_006496.3. [UniGene 139588 - Hs.73799]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001091470.1 PREDICTED: guanine nucleotide-binding protein G(k) subunit alpha M. mulatta 100.0 353
XP_003892383.1 PREDICTED: guanine nucleotide-binding protein G(k) subunit alpha P. anubis 100.0 353
XP_513624.1 PREDICTED: guanine nucleotide-binding protein G(k) subunit alpha P. troglodytes 100.0 353
NP_006487.1 GNAI3 gene product H. sapiens 100.0 353
XP_001494940.1 PREDICTED: guanine nucleotide-binding protein G(k) subunit alpha E. caballus 100.0 353
NP_001116589.1 GNAI3 gene product S. scrofa 99.7 353
XP_002715849.1 PREDICTED: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3-like O. cuniculus 99.7 353
NP_034436.1 Gnai3 gene product M. musculus 99.2 353
NP_001084365.1 guanine nucleotide-binding protein G(i) subunit alpha-1 X. laevis 96.3 353
NP_957265.1 gnai1 gene product D. rerio 95.2 353
NP_477502.1 G protein alphai subunit 65A D. melanogaster 83.4 354
NP_492108.1 Protein GOA-1 C. elegans 76.0 353
XP_957133.1 guanine nucleotide-binding protein alpha subunit N. crassa 62.5 352
NP_011868.1 Gpa1p S. cerevisiae 54.5 244
NP_180198.1 guanine nucleotide-binding protein alpha-1 subunit A. thaliana 46.5 217
Other hits (2 of 55) [Show all]SpeciesId(%)Len(aa)
NP_037238.1 Gnai3 gene product R. norvegicus 99.4 353
XP_001372511.1 PREDICTED: guanine nucleotide-binding protein G(k) subunit alpha M. domestica 99.4 353

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; kidney; testis; skin; vascular; uterus; lung; uncharacterized tissue; connective tissue; embryonic tissue; spleen; blood; placenta; mixed; intestine; pharynx; mouth; prostate; esophagus; thymus; trachea; liver; mammary gland; eye; stomach; lymph; ascites; muscle; larynx; bladder; bone marrow; heart; thyroid; cervix; bone; umbilical cord; pancreas; adrenal gland; ovary; lymph node; ear; parathyroid; pituitary gland; adipose tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p13
UniSTS entry: Chr 1 D1S3364
UniSTS entry: Chr 1 SHGC-75278 [Map Viewer]
UniSTS entry: Chr 1 D1S3455
UniSTS entry: GNAI3
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

J03198.1 Human stimulatory G protein (of receptor-regulated K+ channels) alpha subunit mRNA, complete cds P
J03238.1 Human GTP-binding protein mRNA, complete cds P
NM_006496.3 Homo sapiens guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 (GNAI3), mRNA P
J03005.1 Human alternative guanine nucleotide-binding regulatory protein (G) alpha-inhibitory-subunit mRNA, complete cds P
BT019974.1 Homo sapiens guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 mRNA, complete cds P
BT019973.1 Homo sapiens guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 mRNA, complete cds P
M27543.1 Human guanine nucleotide-binding protein (Gi) alpha subunit mRNA, complete cds P
AK311691.1 Homo sapiens cDNA, FLJ18733 P
AK312252.1 Homo sapiens cDNA, FLJ92547, Homo sapiens guanine nucleotide binding protein (G protein), alphainhibiting activity polypeptide 3 (GNAI3), mRNA P
BC025285.1 Homo sapiens guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3, mRNA (cDNA clone MGC:39207 IMAGE:5433334), complete cds PA
AF493907.1 Homo sapiens guanine nucleotide binding protein alpha i3 (GNAI3) mRNA, complete cds P

EST sequences (10 of 1408) [Show all sequences]

AA954839.1 Clone IMAGE:1574329 kidney 3' read A
AA960967.1 Clone IMAGE:1564165 mixed 3' read A
AA991382.1 Clone IMAGE:1608931 mammary gland 3' read A
AA996019.1 Clone IMAGE:1606832 kidney 3' read A
AI004932.1 Clone IMAGE:1624776 embryonic tissue 3' read A
AI023937.1 Clone IMAGE:1650579 parathyroid 3' read A
AI022225.1 Clone IMAGE:1655067 mixed 3' read
AI033551.1 Clone IMAGE:1655822 mixed 3' read A
AI038964.1 Clone IMAGE:1672770 mixed 3' read
AI039038.1 Clone IMAGE:1657817 embryonic tissue 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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