BCL2-like 11 (apoptosis facilitator) (BCL2L11)

Restricted Expression:

germ cell tumor [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

testis; skin; vascular; muscle; thymus; blood; brain; embryonic tissue; trachea

NCBI

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Finding cDNAs

UGID:5800821 UniGene Hs.737004 Homo sapiens (human) BCL2L11

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BCL2-like 11 (apoptosis facilitator) (BCL2L11)

Human protein-coding gene BCL2L11. Represented by 19 ESTs from 12 cDNA libraries. EST representation biased toward germ cell tumor. [UniGene 5800821 - Hs.737004]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_619532.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	BCL2L11 gene product	H. sapiens	100.0	134
XP_001086237.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: bcl-2-like protein 11	M. mulatta	100.0	131
NP_997563.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Bcl2l11 gene product	M. musculus	93.7	127
Other hits (2 of 5) [Show all]		Species	Id(%)	Len(aa)
XP_003909170.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: bcl-2-like protein 11	P. anubis	96.0	225
XP_003432252.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: bcl-2-like protein 11	C. lupus familiaris	92.4	130

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	2
	Map position:	2q13

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (2)

	AB071200.1	Homo sapiens mRNA for Bim-beta4, complete cds
	AB071198.1	Homo sapiens mRNA for Bim-beta2, complete cds	P

EST sequences (10 of 19) [Show all sequences]

BX282330.1	Clone IMAGp998L0211536_;_IMAGE:5213713	blood		P
CN411912.1		embryonic tissue	5' read	P
DN999398.1	Clone TC110110	vascular	5' read	P
DA021592.1	Clone ASTRO2003312	brain	5' read	P
DA476330.1	Clone DFNES2005359	skin	5' read	P
DA675854.1	Clone NETRP2006851	blood	5' read	P
DA758136.1	Clone NT2RP8005774	testis	5' read	P
DA758175.1	Clone NT2RP8005822	testis	5' read	P
DA798191.1	Clone OCBBF3001508	brain	5' read
DA893786.1	Clone SKMUS2000950	muscle	5' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria