> X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3)
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UGID:5797229     UniGene Hs.733412     Homo sapiens (human)   XRCC3 Order cDNA clone, Links
X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3)

Human protein-coding gene XRCC3. Represented by 238 ESTs from 118 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 5797229 - Hs.733412]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003314577.1 PREDICTED: DNA repair protein XRCC3 isoform 1 P. troglodytes 100.0 345
NP_001093588.1 XRCC3 gene product H. sapiens 100.0 345
NP_083151.1 Xrcc3 gene product M. musculus 78.8 348
NP_001079887.1 X-ray repair complementing defective repair in Chinese hamster cells 3 X. laevis 63.6 343
NP_001013559.1 xrcc3 gene product D. rerio 59.4 347
Other hits (2 of 20) [Show all]SpeciesId(%)Len(aa)
XP_001083970.1 PREDICTED: DNA repair protein XRCC3 isoform 2 M. mulatta 97.7 345
XP_003902365.1 PREDICTED: DNA repair protein XRCC3 P. anubis 97.4 345

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; brain; testis; embryonic tissue; placenta; uterus; lymph node; pancreas; kidney; lymph; skin; cervix; lung; mammary gland; connective tissue; mouth; vascular; tonsil; eye; muscle; spleen; intestine; blood; ascites; prostate; mixed; thymus; heart; bone marrow; adrenal gland; nerve; liver; ganglia; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 14
Map position: 14q32.3
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BX161398.1 human full-length cDNA clone CS0DC014YE11 of Neuroblastoma of Homo sapiens (human) P
BT007417.1 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 mRNA, complete cds P
AK124498.1 Homo sapiens cDNA FLJ42507 fis, clone BRACE2040514, highly similar to DNA-repair protein XRCC3 P
NM_005432.3 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 2, mRNA PA
AK022829.1 Homo sapiens cDNA FLJ12767 fis, clone NT2RP2001536, highly similar to DNA-repair protein XRCC3 P
AK023646.1 Homo sapiens cDNA FLJ13584 fis, clone PLACE1009113, highly similar to DNA-repair protein XRCC3 P
BC002949.1 Homo sapiens, clone IMAGE:3543559, mRNA, partial cds A
BC001036.1 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3, mRNA (cDNA clone MGC:1435 IMAGE:3139703), complete cds PA
BC011725.2 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3, mRNA (cDNA clone MGC:19630 IMAGE:4138588), complete cds PA
NM_001100119.1 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 1, mRNA PA
NM_001100118.1 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 3, mRNA PA
AK296465.1 Homo sapiens cDNA FLJ53535 complete cds
AF035586.1 Homo sapiens X-ray repair cross-complementing protein 3 (XRCC3) mRNA, complete cds PA

EST sequences (10 of 238) [Show all sequences]

CB048578.1 Clone IMAGE:3271046 prostate 3' read
CB048579.1 Clone IMAGE:3271046 prostate 5' read
CB153641.1 Clone B1T694954-26-A07 brain 5' read
CB150648.1 Clone C1SNU17-32-F02 cervix 5' read
AI571318.1 Clone IMAGE:2170512 brain 3' read P
AL044657.1 Clone DKFZp434A1835 testis 5' read P
BX347451.2 Clone CS0DL010YN23 uncharacterized tissue 5' read P
BX368252.2 Clone CS0DL006YG24 uncharacterized tissue 5' read
BX385077.2 Clone CS0DL006YG24 uncharacterized tissue 3' read
BX385078.2 Clone CS0DL006YG24 uncharacterized tissue 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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