> Adenylate kinase 3 (AK3)
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UGID:5795839     UniGene Hs.732022     Homo sapiens (human)   AK3 Links
Adenylate kinase 3 (AK3)

Human protein-coding gene AK3. Represented by 435 ESTs from 212 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 5795839 - Hs.732022]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_057366.2 AK3 gene product H. sapiens 100.0 226
XP_001138039.2 PREDICTED: GTP:AMP phosphotransferase, mitochondrial isoform 4 P. troglodytes 100.0 181
XP_001084982.1 PREDICTED: GTP:AMP phosphotransferase mitochondrial-like isoform 2 M. mulatta 99.6 226
XP_003911793.1 PREDICTED: GTP:AMP phosphotransferase, mitochondrial isoform 1 P. anubis 99.6 226
NP_067274.1 GTP:AMP phosphotransferase, mitochondrial M. musculus 95.2 226
NP_001084561.1 uncharacterized protein LOC414511 X. laevis 79.4 217
NP_998295.2 GTP:AMP phosphotransferase, mitochondrial D. rerio 69.7 221
NP_524312.1 adenylate kinase-3, isoform A D. melanogaster 55.2 212
NP_201145.1 adenylate kinase 1 A. thaliana 46.7 197
NP_498730.1 Protein LET-754 C. elegans 46.4 194
NP_011097.3 adenylate kinase ADK2 S. cerevisiae 46.1 206
Other hits (2 of 49) [Show all]SpeciesId(%)Len(aa)
XP_853049.3 PREDICTED: GTP:AMP phosphotransferase, mitochondrial C. lupus familiaris 96.0 226
NP_001075583.1 LOC100008827 gene product O. cuniculus 96.0 226

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; spleen; skin; testis; heart; kidney; pharynx; thymus; uncharacterized tissue; liver; lung; embryonic tissue; connective tissue; uterus; pancreas; mixed; adrenal gland; vascular; ovary; eye; intestine; adipose tissue; muscle; parathyroid; stomach; thyroid; cervix; bone marrow; mouth; blood; salivary gland; mammary gland; ascites; nerve; bone; prostate; lymph node; bladder; trachea; lymph
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9p24.1
UniSTS entry: Chr 8 GDB:451685
UniSTS entry: Chr 9 RH69564
UniSTS entry: Chr 9 SHGC-64759
UniSTS entry: Chr 9 RH69311
UniSTS entry: Chr 9 RH93015
UniSTS entry: Chr 9 D9S987E
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 1 D11S3114
UniSTS entry: Chr 1 D8S2278
UniSTS entry: Chr 1 sY3084
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

AF100785.1 Homo sapiens GTP:AMP phosphotransferase mRNA, complete cds; nuclear gene encoding mitochondrial product PA
AF086913.1 Homo sapiens GTP:ATP phosphotransferase mRNA, complete cds P
BX640794.1 Homo sapiens mRNA; cDNA DKFZp686M14193 (from clone DKFZp686M14193) A
AK124824.1 Homo sapiens cDNA FLJ42834 fis, clone BRCAN2019002, highly similar to GTP:AMP phosphotransferase mitochondrial (EC 2.7.4.10) P
AB021870.1 Homo sapiens hAK3alpha mRNA for adenylate kinase 3 alpha, complete cds P
AK001553.1 Homo sapiens cDNA FLJ10691 fis, clone NT2RP3000359, highly similar to GTP:AMP PHOSPHOTRANSFERASE MITOCHONDRIAL (EC 2.7.4.10) P
AK001951.1 Homo sapiens cDNA FLJ11089 fis, clone PLACE1005305, highly similar to GTP:AMP PHOSPHOTRANSFERASE MITOCHONDRIAL (EC 2.7.4.10) P
NM_016282.3 Homo sapiens adenylate kinase 3 (AK3), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA PA
AF183419.1 Homo sapiens GTP:AMP phosphotransferase mRNA, complete cds; nuclear gene for mitochondrial product PA
AK027534.1 Homo sapiens cDNA FLJ14628 fis, clone NT2RP2000329, highly similar to GTP:AMP PHOSPHOTRANSFERASE MITOCHONDRIAL (EC 2.7.4.10) P
BC013771.1 Homo sapiens adenylate kinase 3, mRNA (cDNA clone MGC:21124 IMAGE:4385034), complete cds PA
AK098205.1 Homo sapiens cDNA FLJ40886 fis, clone UTERU2000663, highly similar to GTP:AMP phosphotransferase mitochondrial (EC 2.7.4.10) P
AK298200.1 Homo sapiens cDNA FLJ58032 complete cds, highly similar to GTP:AMP phosphotransferase mitochondrial (EC 2.7.4.10) P
NM_001199856.1 Homo sapiens adenylate kinase 3 (AK3), transcript variant 6, mRNA PA
NM_001199855.1 Homo sapiens adenylate kinase 3 (AK3), transcript variant 5, mRNA PA
NM_001199853.1 Homo sapiens adenylate kinase 3 (AK3), transcript variant 3, mRNA PA
NM_001199852.1 Homo sapiens adenylate kinase 3 (AK3), transcript variant 2, mRNA PA

EST sequences (10 of 435) [Show all sequences]

AA969728.1 Clone IMAGE:1579225 mixed 3' read A
AA993680.1 Clone IMAGE:1624681 embryonic tissue 3' read A
AI022539.1 Clone IMAGE:1651007 parathyroid 3' read A
AI038657.1 Clone IMAGE:1658734 embryonic tissue 3' read A
AI052134.1 Clone IMAGE:1667331 parathyroid 3' read A
AI056436.1 Clone IMAGE:1669270 brain 3' read
AI089644.1 Clone IMAGE:1696468 uterus 3' read A
AI095714.1 Clone IMAGE:1697226 uterus 3' read A
BX111262.1 Clone IMAGp998L031206_;_IMAGE:505490 uterus A
AI262833.1 Clone IMAGE:1871023 intestine 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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