Makorin ring finger protein 3 (MKRN3)

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UGID:139531 UniGene Hs.72964 Homo sapiens (human) MKRN3

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Makorin ring finger protein 3 (MKRN3)

Human protein-coding gene MKRN3. Represented by 32 ESTs from 24 cDNA libraries. Corresponds to reference sequence NM_005664.3. [UniGene 139531 - Hs.72964]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_005655.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	MKRN3 gene product	H. sapiens	100.0	506
XP_510258.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: probable E3 ubiquitin-protein ligase makorin-3	P. troglodytes	99.8	506
NP_035876.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Mkrn3 gene product	M. musculus	64.0	543
NP_001086242.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	probable E3 ubiquitin-protein ligase makorin-1	X. laevis	51.3	372
NP_694510.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	mkrn1 gene product	D. rerio	50.7	423
Other hits (2 of 19) [Show all]		Species	Id(%)	Len(aa)
XP_001106523.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: probable E3 ubiquitin-protein ligase makorin-3	M. mulatta	95.7	506
XP_003900711.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: probable E3 ubiquitin-protein ligase makorin-3	P. anubis	95.7	506

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; uncharacterized tissue; placenta; muscle; esophagus; liver; mixed; skin; prostate; blood

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	15
Map position:	15q11-q13
UniSTS entry:	Chr 15	SHGC-35648	[Map Viewer]

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (3)

BC044639.1	Homo sapiens makorin ring finger protein 3, mRNA (cDNA clone MGC:52220 IMAGE:4140028), complete cds	PA
NM_005664.3	Homo sapiens makorin ring finger protein 3 (MKRN3), mRNA	PA
AK309383.1	Homo sapiens cDNA, FLJ99424	P

EST sequences (10 of 32) [Show all sequences]

AI497659.1	Clone IMAGE:2163194	brain	3' read
AI494223.1	Clone IMAGE:2019965	brain	3' read
AI553882.1	Clone IMAGE:2169114	brain	3' read	P
AI936618.1	Clone IMAGE:2329619	mixed	3' read
AI939624.1	Clone IMAGE:2163194	brain	3' read
AW292378.1	Clone IMAGE:2725702	uncharacterized tissue	3' read	P
AW445166.1	Clone IMAGE:2733750	uncharacterized tissue	3' read
AW952653.1		uncharacterized tissue
BE728344.1	Clone IMAGE:3831272	skin	5' read	P
DR003638.1	Clone TC116581	brain	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria