Hypermethylated in cancer 1 (HIC1)

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UGID:139530 UniGene Hs.72956 Homo sapiens (human) HIC1

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Hypermethylated in cancer 1 (HIC1)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_001091672.1	hypermethylated in cancer 1 isoform 2	H. sapiens	100.0	732
NP_001091673.1	hypermethylated in cancer 1 isoform 2	M. musculus	97.7	732
NP_001002314.1	hypermethylated in cancer 1	D. rerio	63.9	736
NP_001090444.1	hypermethylated in cancer 2	X. laevis	48.9	448

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	skin; uncharacterized tissue; mixed; prostate; cervix; bone marrow; vascular; pancreas; eye; ovary; kidney; testis; embryonic tissue; connective tissue; bone

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	17
Map position:	17p13.3
UniSTS entry:	Chr 17	RH78924
UniSTS entry:	Chr 17	(n/a)
UniSTS entry:	Chr 17	G54870
UniSTS entry:	Chr 17	G54752
UniSTS entry:	Chr 17	G54875
UniSTS entry:	Chr 17	G54864
UniSTS entry:	Chr 17	G54874
UniSTS entry:	Chr 17	G54871
UniSTS entry:	Chr 17	G54868
UniSTS entry:	Chr 17	G54872

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

NM_006497.3	Homo sapiens hypermethylated in cancer 1 (HIC1), transcript variant 1, mRNA	PA
AJ550616.1	Homo sapiens partial mRNA for hypermethylated in cancer 1 (HIC1 gene)	P
DQ187313.1	Homo sapiens truncated HIC1 protein (HIC1) mRNA, complete cds	P
NM_001098202.1	Homo sapiens hypermethylated in cancer 1 (HIC1), transcript variant 2, mRNA	PA
BC030208.1	Homo sapiens hypermethylated in cancer 1, mRNA (cDNA clone IMAGE:5207336), partial cds	P

EST sequences (10 of 31) [Show all sequences]

AA971486.1	Clone IMAGE:1583261	mixed	3' read	P
AA991668.1	Clone IMAGE:1622002	embryonic tissue	3' read
AA910862.1	Clone IMAGE:1520744	kidney	3' read
AI073751.1	Clone IMAGE:1665179	skin	3' read
AI201273.1	Clone IMAGE:1754925	testis	3' read	A
AI391567.1	Clone IMAGE:2108917	uncharacterized tissue	3' read	P
AI420129.1	Clone IMAGE:2095296	prostate	3' read	A
AI478432.1	Clone IMAGE:2160948	kidney	3' read	P
AI523046.1	Clone IMAGE:2128714	vascular	3' read	P
BX280170.1	Clone IMAGp998I0511442_;_IMAGE:5177548	mixed		P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria