> Sequestosome 1 (SQSTM1)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:4030210     UniGene Hs.724025     Homo sapiens (human)   SQSTM1 Order cDNA clone, Links
Sequestosome 1 (SQSTM1)

Human protein-coding gene SQSTM1. Represented by 3854 ESTs from 654 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 4030210 - Hs.724025]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001153075.1 PREDICTED: sequestosome-1 isoform 10 P. troglodytes 100.0 439
NP_003891.1 SQSTM1 gene product H. sapiens 100.0 439
XP_003900678.1 PREDICTED: sequestosome-1 P. anubis 99.5 439
XP_001102347.1 PREDICTED: sequestosome-1 isoform 3 M. mulatta 99.5 438
NP_035148.1 Sqstm1 gene product M. musculus 96.8 441
NP_001079920.1 sequestosome 1 X. laevis 66.2 452
NP_998338.1 sqstm1 gene product D. rerio 61.3 287
Other hits (2 of 18) [Show all]SpeciesId(%)Len(aa)
XP_003123687.1 PREDICTED: sequestosome-1-like S. scrofa 97.3 439
NP_001156515.1 SQSTM1 gene product O. aries 97.0 439

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; skin; lung; mammary gland; placenta; ovary; pancreas; uterus; liver; intestine; testis; kidney; eye; uncharacterized tissue; prostate; thyroid; mixed; connective tissue; ascites; bone marrow; stomach; blood; salivary gland; adrenal gland; cervix; embryonic tissue; heart; bone; spleen; muscle; thymus; mouth; bladder; vascular; ear; tonsil; pituitary gland; lymph; adipose tissue; ganglia; trachea; esophagus; lymph node; epididymis; parathyroid; amniotic fluid; nerve; larynx; umbilical cord; pharynx; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5q35
UniSTS entry: Chr 5 A002O27
UniSTS entry: Chr 5 RH18060
UniSTS entry: Chr 5 D5S2306E
UniSTS entry: Chr 5 SGC31697 [Map Viewer]
UniSTS entry: Chr 5 A008T21
UniSTS entry: Chr 5 SHGC-33017
UniSTS entry: Chr 12 TMSB4X
UniSTS entry: SQSTM1
UniSTS entry: Chr 20 MARC_4921-4922:991938931:1
UniSTS entry: Chr 1 SHGC-182
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

BC050631.1 Homo sapiens sequestosome 1, mRNA (cDNA clone IMAGE:3897870), **** WARNING: chimeric clone **** PA
NM_003900.4 Homo sapiens sequestosome 1 (SQSTM1), transcript variant 1, mRNA PA
AK025146.1 Homo sapiens cDNA: FLJ21493 fis, clone COL05558, highly similar to HSU46751 Human phosphotyrosine independent ligand p62 for the Lck SH2 domain mRNA PA
U41806.1 Human EBI3-associated protein p60 mRNA, complete cds P
BC001874.1 Homo sapiens sequestosome 1, mRNA (cDNA clone MGC:1276 IMAGE:3535436), complete cds PA
BC000951.2 Homo sapiens, Similar to sequestosome 1, clone IMAGE:3449348, mRNA, partial cds PA
AK226167.1 Homo sapiens mRNA for sequestosome 1 variant, clone: bm01376 PA
U46751.1 Human phosphotyrosine independent ligand p62 for the Lck SH2 domain mRNA, complete cds PA
BC003139.1 Homo sapiens sequestosome 1, mRNA (cDNA clone MGC:3682 IMAGE:2906264), complete cds PA
BC005857.2 Homo sapiens sequestosome 1, mRNA (cDNA clone IMAGE:3029863) PA
BC017222.1 Homo sapiens sequestosome 1, mRNA (cDNA clone MGC:14328 IMAGE:4298142), complete cds PA
BC019111.1 Homo sapiens sequestosome 1, mRNA (cDNA clone MGC:29719 IMAGE:5091391), complete cds PA
AK312451.1 Homo sapiens cDNA, FLJ92806, Homo sapiens sequestosome 1 (SQSTM1), mRNA P
AK096257.1 Homo sapiens cDNA FLJ38938 fis, clone NT2NE2015626
AK093109.1 Homo sapiens cDNA FLJ35790 fis, clone TESTI2005720
AK304877.1 Homo sapiens cDNA FLJ52854 complete cds, highly similar to Sequestosome-1 P
NM_001142299.1 Homo sapiens sequestosome 1 (SQSTM1), transcript variant 3, mRNA PA
NM_001142298.1 Homo sapiens sequestosome 1 (SQSTM1), transcript variant 2, mRNA PA

EST sequences (10 of 3854) [Show all sequences]

AA954704.1 Clone IMAGE:1572858 kidney 3' read A
AA976331.1 Clone IMAGE:1589578 kidney 3' read A
AA976947.1 Clone IMAGE:1587889 uncharacterized tissue 3' read A
AA978037.1 Clone IMAGE:1590278 kidney 3' read A
AA995848.1 Clone IMAGE:1611951 uncharacterized tissue 3' read A
AA906641.1 Clone IMAGE:1522049 lung 3' read
AI003196.1 Clone IMAGE:1685362 brain 3' read P
AI005047.1 Clone IMAGE:1635173 kidney 3' read A
AI017485.1 Clone IMAGE:1627664 mixed 3' read A
AI022867.1 Clone IMAGE:1650646 parathyroid 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help