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UGID:130815     UniGene Hs.724     Homo sapiens (human)   THRA Order cDNA clone, Links
Thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) (THRA)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_003241.2 thyroid hormone receptor, alpha isoform 2 H. sapiens 100.0 489
NP_999355.1 thyroid hormone receptor, alpha S. scrofa 100.0 409
XP_001478999.1 PREDICTED: similar to thyroid hormone receptor M. musculus 99.8 409
NP_001094389.1 thyroid hormone receptor alpha1 O. aries 99.8 409
XP_851167.1 PREDICTED: similar to Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7) isoform 2 C. lupus familiaris 99.6 496
NP_112396.2 c-erbA-alpha2 isoform TRalpha2 R. norvegicus 99.6 491
NP_001081595.1 thyroid hormone receptor X. laevis 92.6 417
NP_571471.1 thyroid hormone receptor alpha a D. rerio 90.3 404

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; spinal cord; eye; ovary; intestine; pancreas; ear; kidney; mammary gland; thyroid; placenta; salivary gland; uterus; mixed; muscle; prostate; testis; lung; heart; embryonic tissue; connective tissue; cervix; spleen; pituitary gland; stomach; skin; liver; ascites; bladder; nerve; ganglia; bone; blood; parathyroid; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17q11.2
UniSTS entry: Chr 17 RH110
UniSTS entry: Chr 17 D10S2160
UniSTS entry: Chr 17 (n/a)
UniSTS entry: Chr 17 (n/a)
UniSTS entry: Chr 17 (n/a)
UniSTS entry: Chr 17 (n/a)
UniSTS entry: Chr 17 GDB:180966
UniSTS entry: Chr 17 GDB:196130
UniSTS entry: Chr 17 (n/a)
UniSTS entry: Chr 17 D17S1979
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (21)

NM_003250.4 Homo sapiens thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) (THRA), transcript variant 2, mRNA PA
BC062421.1 Homo sapiens cDNA clone IMAGE:6500508, partial cds A
NM_199334.2 Homo sapiens thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) (THRA), transcript variant 1, mRNA PA
CR541915.1 Homo sapiens full open reading frame cDNA clone RZPDo834E0733D for gene THRA, thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian); complete cds, without stopcodon P
CR602782.1 full-length cDNA clone CS0DB003YL08 of Neuroblastoma Cot 10-normalized of Homo sapiens (human) P
CR596083.1 full-length cDNA clone CS0DK010YD06 of HeLa cells Cot 25-normalized of Homo sapiens (human) P
AB209346.1 Homo sapiens mRNA for thyroid hormone receptor, alpha isoform 1 variant protein P
M24900.1 Human triiodothyronine recptor (THRA1, ear1), and ear2 genes, last 2 exons each P
BC002728.2 Homo sapiens thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian), mRNA (cDNA clone MGC:3645 IMAGE:3628335), complete cds PA
BC000261.1 Homo sapiens thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian), mRNA (cDNA clone MGC:2353 IMAGE:3501886), complete cds PA
J03239.1 Human c-erbA-alpha-2 gene encoding thyroid hormone receptor type alpha-2 mRNA, complete cds, clone hTR-alpha-2 P
BC008851.2 Homo sapiens thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian), mRNA (cDNA clone MGC:14305 IMAGE:4137980), complete cds PA
AK290071.1 Homo sapiens cDNA FLJ75155 complete cds, highly similar to Homo sapiens thyroid hormone receptor, alpha (erythroblasticleukemia viral (v-erb-a) oncogene homolog, avian) (THRA),transcript variant 1, mRNA P
AK290530.1 Homo sapiens cDNA FLJ75491 complete cds, highly similar to Homo sapiens thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) (THRA), transcript variant 2, mRNA P
AK311344.1 Homo sapiens cDNA, FLJ18386 P
X55005.1 Homo sapiens mRNA for thyroid hormone receptor alpha 1 THRA1, (c-erbA-1 gene) PA
Y00479.1 H.sapiens mRNA for thyroid hormone receptor P
AF522368.1 Homo sapiens thyroid hormone receptor alpha3 mRNA, partial cds P
AB307686.1 Homo sapiens NR1A1 mRNA for thyroid hormone receptor alpha, complete cds P
BC035137.1 Homo sapiens thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian), mRNA (cDNA clone MGC:43240 IMAGE:5264048), complete cds PA
M24899.1 Human triiodothyronine (ear7) mRNA, complete cds P

EST sequences (10 of 396) [Show all sequences]

AI003984.1 Clone IMAGE:1625169 embryonic tissue 3' read
AI144477.1 Clone IMAGE:1705756 heart 3' read A
CB050954.1 Clone IMAGE:3289338 prostate 5' read P
CB050953.1 Clone IMAGE:3289338 prostate 3' read A
CB054874.1 Clone IMAGE:3291789 brain 5' read
CB054873.1 Clone IMAGE:3291789 brain 3' read A
AI160845.1 Clone IMAGE:1704990 heart 3' read
AI276376.1 Clone IMAGE:1990579 uterus 3' read A
AI084142.1 Clone IMAGE:1750898 brain 3' read
AI364089.1 Clone IMAGE:2016713 brain 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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