> Major histocompatibility complex, class II, DR beta 4 (HLA-DRB4)
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UGID:3548337     UniGene Hs.716081     Homo sapiens (human)   HLA-DRB4 Links
Major histocompatibility complex, class II, DR beta 4 (HLA-DRB4)

Human protein-coding gene HLA-DRB4. Represented by 13 ESTs from 10 cDNA libraries. EST representation biased toward lymphoma. [UniGene 3548337 - Hs.716081]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003846510.1 PREDICTED: HLA class II histocompatibility antigen, DR beta 3 chain isoform 1 H. sapiens 89.1 239
NP_034512.2 H2-Eb1 gene product M. musculus 63.7 234
NP_001177324.1 uncharacterized protein LOC100462907 precursor X. laevis 51.5 134
Other hits (2 of 12) [Show all]SpeciesId(%)Len(aa)
NP_001037726.1 MAMU-DRB1 gene product M. mulatta 79.1 239
XP_001165809.3 PREDICTED: HLA class II histocompatibility antigen, DR beta 5 chain isoform 8 P. troglodytes 76.2 239

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: lymphoma [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: blood; lymph; brain; intestine; tonsil; mixed; vascular; lung
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Map position: 6p21.3
UniSTS entry: Chr 6 GDB:177509
UniSTS entry: Chr 6 GDB:362790
UniSTS entry: RH76259
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

S48645.1 HLA-DRB1 (DRw12)=MHC class II antigen {first domain} [human, mRNA Partial, 282 nt] P
U47028.1 Human MHC class II HLA-DR-beta (DRB1*0308 allele) mRNA, partial cds P
U29342.1 Human MHC class II antigen HLA-DR-beta (DRB1 03022 allele) mRNA, partial cds P
M16732.1 Human MHC class II HLA-DR4/w53 first domain coding region fo DR-beta chain mRNA (Dw4) P
M15071.1 Human MHC class II HLA-DR-beta-2 chain mRNA (DR4,Dw15), partial cds P
M17388.1 Human MHC class II HLA-DR-beta mRNA (DR9), partial cds
M14190.1 Human MHC class II DR7-beta-1 chain mRNA (DR7), partial cds P
FR773882.1 Homo sapiens partial HLA-DRB1 gene for MHC class II antigen, allele HLA-DRB1*11new, exon 2, clone UK Essen DNA117975 P

EST sequences (13)

CB957330.1 Clone IMAGE:30353892 mixed 5' read
CD511623.1 Clone IMAGE:30405448 vascular 5' read PA
BF082950.1 intestine P
BF342032.1 Clone IMAGE:4152208 brain 5' read
DA813717.1 Clone PEBLM2000749 blood 5' read P
BF797132.1 Clone IMAGE:4341239 lymph 5' read
BF975444.1 Clone IMAGE:4336963 tonsil 5' read
BG485529.1 Clone IMAGE:4618805 lung 5' read P
BG754363.1 Clone IMAGE:4846403 tonsil 5' read
BG759843.1 Clone IMAGE:4852092 tonsil 5' read P
BM459340.1 Clone IMAGE:5495900 lymph 5' read P
BM919996.1 Clone IMAGE:5749826 mixed 5' read P
BQ057137.1 Clone IMAGE:5812319 lymph 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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