> Recombination activating gene 2 (RAG2)
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UGID:3370099     UniGene Hs.714519     Homo sapiens (human)   RAG2 Order cDNA clone, Links
Recombination activating gene 2 (RAG2)

Human protein-coding gene RAG2. Represented by 86 ESTs from 16 cDNA libraries. EST representation biased toward thymus. Corresponds to 3 reference sequences (different isoforms). [UniGene 3370099 - Hs.714519]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000527.2 RAG2 gene product H. sapiens 100.0 526
XP_001155150.1 PREDICTED: V(D)J recombination-activating protein 2 isoform 1 P. troglodytes 99.6 526
NP_033046.1 Rag2 gene product M. musculus 89.6 526
NP_001091369.1 V(D)J recombination-activating protein 2 X. laevis 62.3 519
NP_571460.2 rag2 gene product D. rerio 54.0 529
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
XP_001114734.2 PREDICTED: V(D)J recombination-activating protein 2 isoform 1 M. mulatta 98.5 531
XP_003910067.1 PREDICTED: V(D)J recombination-activating protein 2 isoform 1 P. anubis 98.5 531

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: thymus [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: thymus; testis; uncharacterized tissue; lymph node; mixed; heart
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p13
UniSTS entry: Chr 11 RAG2
UniSTS entry: Chr 11 RAG2_V121
UniSTS entry: RAG2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

AF080577.1 Homo sapiens RAG2 mRNA, partial cds P
NM_000536.3 Homo sapiens recombination activating gene 2 (RAG2), transcript variant 1, mRNA PA
BC022397.1 Homo sapiens recombination activating gene 2, mRNA (cDNA clone MGC:24118 IMAGE:4656700), complete cds PA
AK292664.1 Homo sapiens cDNA FLJ75861 complete cds, highly similar to Homo sapiens recombination activating gene 2 (RAG2), mRNA P
S78372.1 RAG2=recombination activation gene 2 [human, bone marrow, mRNA Partial, 148 nt]
NM_001243786.1 Homo sapiens recombination activating gene 2 (RAG2), transcript variant 4, mRNA PA
NM_001243785.1 Homo sapiens recombination activating gene 2 (RAG2), transcript variant 3, mRNA PA

EST sequences (10 of 86) [Show all sequences]

T25429.1 thymus
T25437.1 thymus
BX457365.2 Clone CS0CAP007YP02 thymus 5' read P
AW058148.1 Clone IMAGE:2535989 thymus 3' read A
AW629088.1 Clone IMAGE:2975668 mixed 3' read PA
BE245876.1 Clone TCBAP3432 lymph node
BE247239.1 Clone TCBAP3851 lymph node P
BE247400.1 Clone TCBAP3495 lymph node
DA536717.1 Clone FEHRT2002297 heart 5' read P
DB042868.1 Clone TESTI2030335 testis 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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