> REX2, RNA exonuclease 2 homolog (S. cerevisiae) (REXO2)
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UGID:3355671     UniGene Hs.714231     Homo sapiens (human)   REXO2
REX2, RNA exonuclease 2 homolog (S. cerevisiae) (REXO2)

Human protein-coding gene REXO2. Represented by 448 ESTs from 179 cDNA libraries. Corresponds to reference sequence NM_015523.3. [UniGene 3355671 - Hs.714231]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001087552.1 PREDICTED: oligoribonuclease, mitochondrial-like isoform 1 M. mulatta 100.0 236
XP_003910782.1 PREDICTED: oligoribonuclease, mitochondrial P. anubis 100.0 236
XP_508768.1 PREDICTED: oligoribonuclease, mitochondrial isoform 2 P. troglodytes 100.0 236
NP_056338.2 REXO2 gene product H. sapiens 100.0 236
NP_077195.2 Rexo2 gene product M. musculus 97.5 236
NP_001088822.1 REX2, RNA exonuclease 2 homolog X. laevis 89.7 184
NP_957038.1 smfn gene product D. rerio 85.9 197
XP_001702562.1 predicted protein C. reinhardtii 56.7 179
NP_651184.1 CG10214 D. melanogaster 54.6 173
NP_001031426.1 oligoribonuclease A. thaliana 52.0 178
NP_505606.1 hypothetical protein C08B6.8 C. elegans 47.5 181
Other hits (2 of 50) [Show all]SpeciesId(%)Len(aa)
XP_002708465.1 PREDICTED: small fragment nuclease O. cuniculus 99.2 236
XP_001502237.1 PREDICTED: oligoribonuclease, mitochondrial-like E. caballus 98.7 236

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: connective tissue; testis; brain; lung; embryonic tissue; placenta; heart; stomach; pancreas; mixed; intestine; skin; cervix; uterus; eye; ovary; uncharacterized tissue; pituitary gland; muscle; adrenal gland; salivary gland; blood; mouth; bone; prostate; mammary gland; liver; kidney; amniotic fluid; lymph node; parathyroid; ear; ascites; thyroid; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q23.2
UniSTS entry: Chr 11 STS-H98169
UniSTS entry: Chr 11 STS-AA027991
UniSTS entry: Chr 11 RH91947
UniSTS entry: Chr 11 WI-18173 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AL110239.1 Homo sapiens mRNA; cDNA DKFZp566E144 (from clone DKFZp566E144) PA
BC066947.1 Homo sapiens cDNA clone IMAGE:5263514, containing frame-shift errors PA
CR533500.1 Homo sapiens full open reading frame cDNA clone RZPDo834H0317D for gene DKFZP566E144, small fragment nuclease; complete cds, incl. stopcodon P
NM_015523.3 Homo sapiens REX2, RNA exonuclease 2 homolog (S. cerevisiae) (REXO2), nuclear gene encoding mitochondrial protein, mRNA PA
AF151872.1 Homo sapiens CGI-114 protein mRNA, complete cds P
AK223200.1 Homo sapiens mRNA for small fragment nuclease variant, clone: REC05446 PA
BC107887.1 Homo sapiens REX2, RNA exonuclease 2 homolog (S. cerevisiae), mRNA (cDNA clone MGC:111570 IMAGE:6663083), complete cds PA
BC105026.1 Homo sapiens REX2, RNA exonuclease 2 homolog (S. cerevisiae), mRNA (cDNA clone MGC:132686 IMAGE:8144029), complete cds P
BC105024.1 Homo sapiens REX2, RNA exonuclease 2 homolog (S. cerevisiae), mRNA (cDNA clone MGC:132684 IMAGE:8144027), complete cds P
BC003502.1 Homo sapiens REX2, RNA exonuclease 2 homolog (S. cerevisiae), mRNA (cDNA clone IMAGE:3611742), complete cds PA
AK312042.1 Homo sapiens cDNA, FLJ92319, highly similar to Homo sapiens REX2, RNA exonuclease 2 homolog (S. cerevisiae) (REXO2), mRNA P
BC143701.1 Homo sapiens REX2, RNA exonuclease 2 homolog (S. cerevisiae), mRNA (cDNA clone MGC:177232 IMAGE:9052215), complete cds P

EST sequences (10 of 448) [Show all sequences]

AA911794.1 Clone IMAGE:1519694 uncharacterized tissue 3' read A
AI004436.1 Clone IMAGE:1619956 testis 3' read A
AI017450.1 Clone IMAGE:1635719 kidney 3' read A
AI028092.1 Clone IMAGE:1650323 parathyroid 3' read PA
AI076169.1 Clone IMAGE:1674080 mixed 3' read A
AI094637.1 Clone IMAGE:1670322 brain 3' read A
AI128450.1 Clone IMAGE:1711950 uterus 3' read A
AI128771.1 Clone IMAGE:1691452 heart 3' read A
CB053111.1 Clone IMAGE:3290503 uncharacterized tissue 3' read P
AI149382.1 Clone IMAGE:1721122 uterus 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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