> DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B)
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UGID:3355051     UniGene Hs.713611     Homo sapiens (human)   DNMT3B Links
DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B)

Human protein-coding gene DNMT3B. Represented by 193 ESTs from 65 cDNA libraries. EST representation biased toward blastocyst. Corresponds to 6 reference sequences (different isoforms). [UniGene 3355051 - Hs.713611]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_514580.3 PREDICTED: DNA (cytosine-5)-methyltransferase 3B isoform 5 P. troglodytes 100.0 852
NP_008823.1 DNMT3B gene product H. sapiens 100.0 852
XP_003904916.1 PREDICTED: DNA (cytosine-5)-methyltransferase 3B isoform 1 P. anubis 99.9 852
NP_001003961.2 Dnmt3b gene product M. musculus 90.5 858
NP_001020621.1 dnmt4 gene product D. rerio 75.6 779
Other hits (2 of 25) [Show all]SpeciesId(%)Len(aa)
XP_001107440.2 PREDICTED: DNA (cytosine-5)-methyltransferase 3B isoform 3 M. mulatta 99.2 822
XP_003433293.1 PREDICTED: LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 3B C. lupus familiaris 96.2 842

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: blastocyst [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: embryonic tissue; brain; uncharacterized tissue; testis; placenta; ovary; uterus; pancreas; mammary gland; pharynx; skin; blood; lung; liver; kidney; cervix; intestine; prostate; eye; mixed; larynx; ascites; bone; connective tissue; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20q11.2
UniSTS entry: Chr 20 D20S1126 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (21)

NM_175850.2 Homo sapiens DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B), transcript variant 6, mRNA PA
NM_175849.1 Homo sapiens DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B), transcript variant 3, mRNA PA
NM_175848.1 Homo sapiens DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B), transcript variant 2, mRNA PA
NM_006892.3 Homo sapiens DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B), transcript variant 1, mRNA PA
AK001191.1 Homo sapiens cDNA FLJ10329 fis, clone NT2RM2000594, highly similar to DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) P
AF129267.1 Homo sapiens DNA methyltransferase 3 beta 1 (DNMT3B) mRNA, alternate splice product, partial cds PA
AF129268.1 Homo sapiens DNA methyltransferase 3 beta 4 (DNMT3B) mRNA, alternate splice product, partial cds PA
AF129269.1 Homo sapiens DNA methyltransferase 3 beta 5 (DNMT3B) mRNA, alternate splice product, partial cds PA
AF156487.1 Homo sapiens DNA cytosine-5 methyltransferase 3 beta 3 (DNMT3B) mRNA, complete cds PA
AF156488.1 Homo sapiens DNA cytosine-5 methyltransferase 3 beta 1 (DNMT3B) mRNA, complete cds PA
AF176228.1 Homo sapiens DNA cytosine-5 methyltransferase 3B (DNMT3B) mRNA, complete cds PA
AB208880.1 Homo sapiens mRNA for DNA cytosine-5 methyltransferase 3 beta isoform 6 variant protein P
DQ321787.1 Homo sapiens DNA methyltransferase (DNMT3B) mRNA, DNMT3B-7 allele, complete cds, alternatively spliced P
AF331857.1 Homo sapiens DNA cytosine methyltransferase 3 beta (DNMT3B) mRNA, complete cds P
AK300857.1 Homo sapiens cDNA FLJ60900 complete cds, highly similar to DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) P
AK299915.1 Homo sapiens cDNA FLJ56945 complete cds, highly similar to DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) P
AK299821.1 Homo sapiens cDNA FLJ61375 complete cds, highly similar to Homo sapiens DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B), transcript variant 3, mRNA P
AK299776.1 Homo sapiens cDNA FLJ52873 complete cds, highly similar to DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) P
AK295176.1 Homo sapiens cDNA FLJ57837 complete cds, highly similar to DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) P
NM_001207056.1 Homo sapiens DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B), transcript variant 8, mRNA PA
NM_001207055.1 Homo sapiens DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B), transcript variant 7, mRNA PA

EST sequences (10 of 193) [Show all sequences]

AA887508.1 Clone IMAGE:1500518 lung 3' read
AA923295.1 Clone IMAGE:1550698 uncharacterized tissue 3' read A
AI936519.1 Clone IMAGE:2329509 mixed 3' read
AI868776.1 Clone IMAGE:2149073 mixed 3' read A
BX411256.2 Clone CS0DF007YP21 brain 3' read
AI954642.1 Clone IMAGE:2473178 uncharacterized tissue 3' read
AI971551.1 Clone IMAGE:2479016 uncharacterized tissue 3' read P
CD643397.1 Clone IMAGE:30427414 embryonic tissue 5' read P
CD643566.1 Clone IMAGE:30425130 embryonic tissue 5' read P
CD653499.1 Clone IMAGE:30423666 embryonic tissue 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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