Centromere protein B, 80kDa (CENPB)

Restricted Expression:

adult [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

brain; eye; prostate; vascular; lung; skin; uncharacterized tissue; larynx; placenta; mixed; bone; ascites; connective tissue; stomach

NCBI

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Finding cDNAs

UGID:3350495 UniGene Hs.713340 Homo sapiens (human) CENPB

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Centromere protein B, 80kDa (CENPB)

Human protein-coding gene CENPB. Represented by 30 ESTs from 25 cDNA libraries. EST representation biased toward adult. [UniGene 3350495 - Hs.713340]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_001801.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	CENPB gene product	H. sapiens	100.0	138
NP_031708.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Cenpb gene product	M. musculus	88.5	138
Other hits (2 of 12) [Show all]		Species	Id(%)	Len(aa)
XP_001111455.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: major centromere autoantigen B-like	M. mulatta	99.3	139
XP_003905066.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: major centromere autoantigen B	P. anubis	99.3	139

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	20
	Map position:	20p13

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (1)

AF002714.1

Homo sapiens centromere protein B mRNA, partial cds.

EST sequences (10 of 30) [Show all sequences]

CB050240.1	Clone IMAGE:3271936	prostate	3' read	A
CB050241.1	Clone IMAGE:3271936	prostate	5' read	A
BX104835.1	Clone IMAGp998G02178_;_IMAGE:37772	brain
AI708130.1	Clone IMAGE:2353795	vascular	3' read
AI972471.1	Clone IMAGE:2490125	prostate	3' read
CD579949.2	Clone MPMGp800M06558	brain	5' read
AW068260.1	Clone NHTBC_cn23h11	bone		P
BE255578.1	Clone IMAGE:3352389	eye	5' read	P
BE257983.1	Clone IMAGE:3351390	eye	5' read	P
BE267038.1	Clone IMAGE:3538413	lung	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria