> Programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4)
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UGID:3323697     UniGene Hs.711490     Homo sapiens (human)   PDCD4 Order cDNA clone, Links
Programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4)

Human protein-coding gene PDCD4. Represented by 737 ESTs from 294 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 3323697 - Hs.711490]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001143772.1 PREDICTED: programmed cell death protein 4 isoform 5 P. troglodytes 100.0 468
NP_055271.2 PDCD4 gene product H. sapiens 100.0 468
NP_035180.2 Pdcd4 gene product M. musculus 98.5 468
NP_001080530.1 programmed cell death 4 (neoplastic transformation inhibitor) X. laevis 82.6 454
NP_945329.1 pdcd4b gene product D. rerio 76.0 469
NP_001096977.1 programmed cell death 4 ortholog, isoform B D. melanogaster 47.9 375
Other hits (2 of 37) [Show all]SpeciesId(%)Len(aa)
XP_001086788.1 PREDICTED: programmed cell death protein 4 isoform 3 M. mulatta 99.4 468
XP_003904300.1 PREDICTED: programmed cell death protein 4 isoform 1 P. anubis 99.4 468

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; mammary gland; intestine; blood; esophagus; adrenal gland; uterus; mixed; bone marrow; bladder; spleen; liver; prostate; amniotic fluid; mouth; thyroid; vascular; lung; thymus; trachea; uncharacterized tissue; connective tissue; embryonic tissue; pancreas; kidney; eye; testis; cervix; pharynx; skin; muscle; stomach; ascites; larynx; parathyroid; adipose tissue; pituitary gland; ovary; heart; lymph node; lymph; ganglia; umbilical cord; bone; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q24
UniSTS entry: RH93337
UniSTS entry: Chr 10 MARC_26204-26205:1030736270:1
UniSTS entry: Chr 10 RH44657 [Map Viewer]
UniSTS entry: Chr 10 SHGC-35716 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AL049932.1 Homo sapiens mRNA; cDNA DKFZp564H2416 (from clone DKFZp564H2416) A
BX647834.1 Homo sapiens mRNA; cDNA DKFZp779I201 (from clone DKFZp779I201) PA
NM_014456.4 Homo sapiens programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4), transcript variant 1, mRNA PA
AK223623.1 Homo sapiens mRNA for programmed cell death 4 isoform 1 variant, clone: FCC134E07 P
AK315295.1 Homo sapiens cDNA, FLJ96314, highly similar to Homo sapiens programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4), transcript variant 2, mRNA P
AK312540.1 Homo sapiens cDNA, FLJ92910, highly similar to Homo sapiens programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4), transcript variant 1, mRNA P
BC026104.2 Homo sapiens programmed cell death 4 (neoplastic transformation inhibitor), mRNA (cDNA clone MGC:33046 IMAGE:4798293), complete cds PA
BC031049.1 Homo sapiens programmed cell death 4 (neoplastic transformation inhibitor), mRNA (cDNA clone MGC:33047 IMAGE:5277621), complete cds PA
NM_145341.3 Homo sapiens programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4), transcript variant 2, mRNA PA
AK296753.1 Homo sapiens cDNA FLJ58014 complete cds, highly similar to Homo sapiens programmed cell death 4, transcript variant 1, mRNA P
BC015036.2 Homo sapiens programmed cell death 4 (neoplastic transformation inhibitor), mRNA (cDNA clone IMAGE:3921489), partial cds PA
NM_001199492.1 Homo sapiens programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4), transcript variant 3, mRNA PA
U96628.1 Homo sapiens nuclear antigen H731-like protein mRNA, complete cds P

EST sequences (10 of 737) [Show all sequences]

AA973698.1 Clone IMAGE:1569090 lung 3' read A
AA976891.1 Clone IMAGE:1588344 uncharacterized tissue 3' read A
AI017708.1 Clone IMAGE:1636721 kidney 3' read A
AI038641.1 Clone IMAGE:1658703 embryonic tissue 3' read A
AI077964.1 Clone IMAGE:1668196 parathyroid 3' read A
AI092334.1 Clone IMAGE:1692952 heart 3' read A
AI184858.1 Clone IMAGE:1731999 heart 3' read A
AI185160.1 Clone IMAGE:1740546 lung 3' read A
AI186103.1 Clone IMAGE:1740441 lung 3' read A
AI188327.1 Clone IMAGE:1723594 placenta 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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