> Nitric oxide synthase 2, inducible (NOS2)
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UGID:3321398     UniGene Hs.709191     Homo sapiens (human)   NOS2 Order cDNA clone, Links
Nitric oxide synthase 2, inducible (NOS2)

Human protein-coding gene NOS2. Represented by 86 ESTs from 30 cDNA libraries. EST representation biased toward infant. Corresponds to reference sequence NM_000625.4. [UniGene 3321398 - Hs.709191]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000616.3 NOS2 gene product H. sapiens 100.0 1152
NP_035057.1 Nos2 gene product M. musculus 83.0 1143
NP_001098407.1 nos2a gene product D. rerio 59.9 1070
NP_001079155.1 nitric oxide synthase 1 (neuronal) X. laevis 58.7 1176
NP_001027240.1 nitric oxide synthase, isoform F D. melanogaster 53.5 577
Other hits (2 of 38) [Show all]SpeciesId(%)Len(aa)
XP_001148238.1 PREDICTED: nitric oxide synthase, inducible isoform 2 P. troglodytes 99.4 1152
XP_001106245.1 PREDICTED: nitric oxide synthase, inducible isoform 4 M. mulatta 97.2 1152

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: infant [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; intestine; brain; pancreas; stomach; connective tissue; embryonic tissue; mammary gland; pharynx; trachea; ovary; blood; lung; mixed
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17q11.2-q12
UniSTS entry: GDB:437694
UniSTS entry: Chr 17 PMC151125P1
UniSTS entry: Chr 17 RH79885
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

AF068236.1 Homo sapiens inducible nitric oxide synthase (NOS) mRNA, complete cds P
L24553.1 Homo sapiens inducible nitric oxide synthase mRNA, complete cds P
AB022318.1 Homo sapiens mRNA for inducible nitric oxide synthase, complete cds P
U31511.1 Human inducible nitric oxide synthase (NOS) mRNA, complete cds PA
U05810.1 Human inducible nitric oxide synthase mRNA, complete cds P
L09210.1 Homo sapiens inducible nitric oxide synthase mRNA, complete cds P
NM_000625.4 Homo sapiens nitric oxide synthase 2, inducible (NOS2), mRNA P
U20141.1 Human inducible nitric oxide synthase mRNA, complete cds P
BC130283.1 Homo sapiens nitric oxide synthase 2, inducible, mRNA (cDNA clone MGC:163155 IMAGE:40146314), complete cds P
D26525.1 Homo sapiens mRNA for inducible type of nitric oxide synthase, complete cds P
AK304252.1 Homo sapiens cDNA FLJ60219 complete cds, highly similar to Nitric oxide synthase, inducible (EC 1.14.13.39) P
S75615.1 iNOS=nitric oxide synthase [human, renal proximal tubular cells, mRNA Partial, 283 nt] P
S76479.1 calcium-calmodulin independent nitric oxide synthase iNOS [human, Epstein-Barr virus-transformed Burkitt's lymphoma cell line, Akata, mRNA, 180 nt]
X73029.1 H.sapiens mRNA for nitric oxide synthase P
BC144126.1 Homo sapiens nitric oxide synthase 2, inducible, mRNA (cDNA clone MGC:177663 IMAGE:9052646), complete cds P

EST sequences (10 of 86) [Show all sequences]

BX105931.1 Clone IMAGp998A065231_;_IMAGE:2120333 pancreas A
AI493548.1 Clone IMAGE:2120333 pancreas 3' read
AI652686.1 Clone IMAGE:2307193 uncharacterized tissue 3' read
AI738789.1 Clone IMAGE:2392347 intestine 3' read
AI797675.1 Clone IMAGE:2348360 mixed 3' read
AI953734.1 Clone IMAGE:2474450 uncharacterized tissue 3' read
AI991263.1 Clone IMAGE:2522635 intestine 3' read
AW001205.1 Clone IMAGE:2521119 intestine 3' read
CF540954.1 Clone IMAGE:5843849 connective tissue 3' read A
AW236981.1 Clone IMAGE:2687757 uncharacterized tissue 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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